Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL)

被引：811

作者：

Sarin, Shiv Kumar ^{[1
]}

Kumar, Ashish ^{[2
]}

Almeida, John A. ^{[3
,4
]}

Chawla, Yogesh Kumar ^{[5
]}

Fan, Sheung Tat ^{[6
]}

Garg, Hitendra ^{[1
]}

de Silva, H. Janaka ^{[7
]}

Hamid, Saeed Sadiq ^{[8
]}

Jalan, Rajiv ^{[9
]}

Komolmit, Piyawat ^{[10
]}

Lau, George K. ^{[11
]}

Liu, Qing ^{[12
]}

Madan, Kaushal ^{[2
]}

Mohamed, Rosmawati ^{[13
]}

Ning, Qin ^{[14
]}

Rahman, Salimur ^{[15
]}

Rastogi, Archana ^{[16
]}

Riordan, Stephen M. ^{[3
,4
]}

Sakhuja, Puja ^{[17
]}

Samuel, Didier ^{[18
]}

Shah, Samir ^{[19
]}

Sharma, Barjesh Chander ^{[1
]}

Sharma, Praveen ^{[1
]}

Takikawa, Yasuhiro ^{[20
]}

Thapa, Babu Ram ^{[21
]}

Wai, Chun-Tao ^{[22
]}

Yuen, Man-Fung ^{[11
]}

机构：

[1] Affiliated Univ Delhi, GB Pant Hosp, Dept Gastroenterol, New Delhi 110002, India

[2] ILBS, Dept Hepatol, New Delhi 110070, India

[3] Prince Wales Hosp, Gastrointestinal & Liver Unit, Randwick, NSW 2031, Australia

[4] Univ New S Wales, Randwick, NSW 2031, Australia

[5] Post Grad Inst Med Educ & Res, Dept Hepatol, Chandigarh, India

[6] Univ Hong Kong, Queen Mary Hosp, Dept Surg, Hong Kong, Hong Kong, Peoples R China

[7] Univ Kelaniya, Dept Med, Fac Med, Ragama, Sri Lanka

[8] Aga Khan Univ Hosp, Gastroenterol Sect, Dept Med, Karachi 74800, Pakistan

[9] UCL, Inst Hepatol, Div Med, London WC1E 6HX, England

[10] Chulalongkorn Univ, Dept Med Fac & Med, Bangkok 10330, Thailand

[11] Univ Hong Kong, Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China

[12] Capital Univ Med Sci, Beijing Youan Hosp, Beijing, Peoples R China

[13] Univ Malaya, Dept Med, Fac Med, Kuala Lumpur 50603, Malaysia

[14] Huazhong Univ Sci & Technol, Inst Immunol, Dept Infect Dis, Lab Infect Immunol, Wuhan 430074, Peoples R China

[15] Bangabandhu Sheikh Mujib Med Univ, Dept Hepatol, Dhaka, Bangladesh

[16] ILBS, Dept Pathol, New Delhi 110070, India

[17] Affiliated Univ Delhi, GB Pant Hosp, Dept Pathol, New Delhi 110002, India

[18] INSERM, Hop Paul Brousse, AP HP, Unite 785, F-94800 Villejuif, France

[19] Jaslok Hosp & Res Ctr, Dept Gastroenterol, Mumbai 400026, Maharashtra, India

[20] Iwate Med Univ, Dept Gastroenterol & Hepatol, Morioka, Iwate 0208505, Japan

[21] Post Grad Inst Med Educ & Res, Div Pediat Gastroenterol, Dept Gastroenterol, Chandigarh, India

[22] Gleneagles Hosp, Asian Ctr Liver Dis & Transplantat, Singapore 258500, Singapore

来源：

HEPATOLOGY INTERNATIONAL | 2009年 / 3卷 / 01期

关键词：

Acute-on-chronic liver failure; Acute-on-chronic liver disease; Liver failure; Hepatic failure; Hepatitis; Cirrhosis; B-VIRUS REACTIVATION; ADSORBENT RECIRCULATING SYSTEM; CRITICALLY-ILL PATIENTS; SEVERE VIRAL-HEPATITIS; SHORT-TERM PROGNOSIS; ALBUMIN DIALYSIS; RISK-FACTORS; ASYMMETRIC DIMETHYLARGININE; PATHOPHYSIOLOGICAL BASIS; INFLAMMATORY RESPONSE;

D O I：

10.1007/s12072-008-9106-x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The Asian Pacific Association for the Study of the Liver (APASL) set up a working party on acute-on-chronic liver failure (ACLF) in 2004, with a mandate to develop consensus guidelines on various aspects of ACLF relevant to disease patterns and clinical practice in the Asia-Pacific region. Experts predominantly from the Asia-Pacific region constituted this working party and were requested to identify different issues of ACLF and develop the consensus guidelines. A 2-day meeting of the working party was held on January 22-23, 2008, at New Delhi, India, to discuss and finalize the consensus statements. Only those statements that were unanimously approved by the experts were accepted. These statements were circulated to all the experts and subsequently presented at the Annual Conference of the APASL at Seoul, Korea, in March 2008. The consensus statements along with relevant background information are presented in this review.

引用

页码：269 / 282

页数：14

共 86 条

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