Wilms tumor

被引：48

作者：

Paters, Luke ^{[1
]}

Melchior, Patrick ^{[2
]}

Ruebe, Christian ^{[2
]}

Cooper, Benjamin T. ^{[3
]}

McAleer, Mary Fran ^{[4
]}

Kalapurakal, John A. ^{[5
]}

Paulino, Arnold C. ^{[4
]}

机构：

[1] Univ Cincinnati, Dept Radiat Oncol, Cincinnati, OH USA

[2] Saarland Univ Hosp, Dept Radiat Oncol, Homburg, Germany

[3] NYU, Sch Med, Dept Radiat Oncol, Perlmutter Canc Ctr, New York, NY USA

[4] Univ Texas MD Anderson Canc Ctr, Dept Radiat Oncol, 1515 Holcombe Blvd,Box 97, Houston, TX 77030 USA

[5] Northwestern Univ, Dept Radiat Oncol, Chicago, IL 60611 USA

来源：

PEDIATRIC BLOOD & CANCER | 2021年 / 68卷

关键词：

chemotherapy; radiation therapy; surgery; Wilms tumor; CHILDRENS ONCOLOGY GROUP; RADIATION-THERAPY; STAGE-II; INTERNATIONAL-SOCIETY; INTERMEDIATE-RISK; NEPHRECTOMY; SURVIVAL; RELAPSE; NEPHROBLASTOMA; CHEMOTHERAPY;

D O I：

10.1002/pbc.28257

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The objectives for the treatment of Wilms tumor in both the Children's Oncology Group (COG) and the International Society of Paediatric Oncology (SIOP) have focused on improving cure rates and minimizing toxicity by limiting the use of radiation and doxorubicin. Although the timing of surgery is different in COG (upfront surgery) and SIOP (upfront chemotherapy with delayed surgery), both are effective strategies and have the same survival. Fewer patients are treated with radiotherapy in the SIOP trials but with higher doses. The prognostic significance of biological markers such as 1q gain and clinical outcomes with novel radiation techniques such as intensity modulated radiation therapy will be determined in upcoming clinical trials. A closer collaboration between COG and SIOP could help promote research and improve the clinical outcomes of children with Wilms tumor.

引用

页数：7

共 44 条

[1] Nephron-sparing surgery for Wilms tumor: A systematic review [J].

Berg, Rand N. Wilcox Vanden ;

Bierman, Emily N. ;

Van Noord, Megan ;

Rice, Henry E. ;

Routh, Jonathan C. .

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2016, 34 (01) :24-32

[2] SURVIVAL IN BILATERAL WILMS TUMOR - REVIEW OF 30 NATIONAL WILMS TUMOR STUDY CASES [J].

BISHOP, HC ;

TEFFT, M ;

EVANS, AE ;

DANGIO, GJ .

JOURNAL OF PEDIATRIC SURGERY, 1977, 12 (05) :631-638

[3]

BURGERS JMV, 1986, RADIOTHER ONCOL, V5, P175

[4] A Comparison of Renal Function Outcomes After Nephron-sparing Surgery and Radical Nephrectomy for Nonsyndromic Unilateral Wilms Tumor [J].

Cost, Nicholas G. ;

Sawicz-Birkowska, Krystyna ;

Kajbafzadeh, Abdol-Mohammad ;

Tourchi, Ali ;

Parigi, Gian Battista ;

Guillen, Gabriela ;

DeFoor, W. Robert, Jr. ;

Apoznanski, Wojciech .

UROLOGY, 2014, 83 (06) :1388-1393

[5] A phase 2 study of vincristine and irinotecan in metastatic diffuse anaplastic Wilms tumor: Results from the Children's Oncology Group AREN0321 study. [J].

Daw, Najat C. ;

Anderson, James Robert ;

Hoffer, Fredric A. ;

Geller, James I. ;

Kalapurakal, John A. ;

Perlman, Elizabeth Jones ;

Ehrlich, Peter F. ;

Mullen, Elizabeth Anne ;

Gratias, Eric J. ;

Grundy, Paul Edward ;

Dome, Jeffrey S. .

JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)

[6] Reduction of postoperative chemotherapy in children with stage I intermediate-risk and anaplastic Wilms' tumour (SIOP 93-01 trial): a randomised controlled trial [J].

de Kraker, J ;

Graf, N ;

van Tinteren, H ;

Pein, F ;

Sandstedt, B ;

Godzinski, J ;

Tournade, MF .

LANCET, 2004, 364 (9441) :1229-1235

[7] Treatment of Stage IV Favorable Histology Wilms Tumor With Lung Metastases: A Report From the Children's Oncology Group AREN0533 Study [J].

Dix, David B. ;

Seibel, Nita L. ;

Chi, Yueh-Yun ;

Khanna, Geetika ;

Gratias, Eric ;

Anderson, James R. ;

Mullen, Elizabeth A. ;

Geller, James I. ;

Kalapurakal, John A. ;

Paulino, Arnold C. ;

Perlman, Elizabeth J. ;

Ehrlich, Peter F. ;

Malogolowkin, Marcio ;

Gastier-Foster, Julie M. ;

Wagner, Elizabeth ;

Grundy, Paul E. ;

Fernandez, Conrad V. ;

Dome, Jeffrey S. .

JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (16) :1564-+

[8]

DIX DB, 2015, J CLIN ONCOL S, V33

[9] Results of the First Prospective Multi-institutional Treatment Study in Children With Bilateral Wilms Tumor (AREN0534) A Report From the Children's Oncology Group [J].

Ehrlich, Peter ;

Chi, Yuen Y. ;

Chintagumpala, Murali M. ;

Hoffer, Fred A. ;

Perlman, Elizabeth J. ;

Kalapurakal, John A. ;

Warwick, Ann ;

Shamberger, Robert C. ;

Khanna, Geetika ;

Hamilton, Tom E. ;

Gow, Ken W. ;

Paulino, Arnold C. ;

Gratias, Eric J. ;

Mullen, Elizabeth A. ;

Geller, James I. ;

Grundy, Paul E. ;

Fernandez, Conrad V. ;

Ritchey, Michael L. ;

Dome, James S. .

ANNALS OF SURGERY, 2017, 266 (03) :470-478

[10] Clinicopathologic Findings Predictive of Relapse in Children With Stage III Favorable-Histology Wilms Tumor [J].

Ehrlich, Peter F. ;

Anderson, James R. ;

Ritchey, Michael L. ;

Dome, Jeffrey S. ;

Green, Daniel M. ;

Grundy, Paul E. ;

Perlman, Elizabeth J. ;

Kalapurakal, John A. ;

Breslow, Norman E. ;

Shamberger, Robert C. .

JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (09) :1196-1201

← 1 2 3 4 5 →