Protein folding:: Is hierarchical versus nonhierarchical a productive issue?

被引：4

作者：

Fernández, A ^{[1
]}

机构：

[1] Univ Chicago, Inst Biophys Dynam, Cummings Life Sci Ctr, Chicago, IL 60637 USA

来源：

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS | 2002年 / 19卷 / 05期

关键词：

D O I：

10.1080/07391102.2002.10506781

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A coarse-grained simulation accessing relevant folding timescales for beta-lactoglobulin was corroborated experimentally and reveals a dynamic role for normative structures dictated by local propensity vis-a-vis the large-scale context. This picture prompts us to shift focus, leaving aside the hierarchical vs. nonhierarchical controversy.

引用

页码：735 / 737

页数：3

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