Hybridization chain reaction-based branched rolling circle amplification for chemiluminescence detection of DNA methylation

被引：120
作者：
Bi, Sai [1 ,2 ]
Zhao, Tingting [2 ]
Luo, Baoyu [2 ]
Zhu, Jun-Jie [1 ]
机构：
[1] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Analyt Chem Life Sci, Nanjing 210093, Jiangsu, Peoples R China
[2] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Minist Educ, Key Lab Sensor Anal Tumor Marker, Qingdao 266042, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 61期
基金：
中国国家自然科学基金; 中国博士后科学基金;
关键词：
METHYLTRANSFERASE ACTIVITY; SIGNAL AMPLIFICATION; SENSITIVE DETECTION; COLORIMETRIC ASSAY; LABEL; DNAZYME; INHIBITION; PROTEINS; PLATFORM; SYSTEM;
D O I：
10.1039/c3cc43353f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel hybridization chain reaction-based branched rolling circle amplification combining the fabrication of multi-HRP-capped MNPs is developed for chemiluminescence detection of DNA methyltransferase activities and inhibitors with high sensitivity in a well-controlled manner.
引用
收藏
页码：6906 / 6908
页数：3
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