Electrophilic fluorination using a hypervalent iodine reagent derived from fluoride

被引：84

作者：

Geary, Gemma C. ^{[1
]}

Hope, Eric G. ^{[1
]}

Singh, Kuldip ^{[1
]}

Stuart, Alison M. ^{[1
]}

机构：

[1] Univ Leicester, Dept Chem, Leicester LE1 7RH, Leics, England

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 81期

关键词：

SELECTIVE FLUORINATION; BETA-KETOESTERS; TRIFLUOROMETHYLATION; SELECTFLUOR; AGENTS; SALTS; BIS(TETRAFLUOROBORATE); FAMILY; HF;

D O I：

10.1039/c3cc44792h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The air and moisture stable fluoroiodane 8, readily prepared on a 6 g scale by nucleophilic fluorination of the hydroxyiodane 7 with TREAT-HF, has been used as an electrophilic fluorinating reagent for the first time to monofluorinate 1,3-ketoesters and difluorinate 1,3-diketones in good isolated yields.

引用

页码：9263 / 9265

页数：3

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