A critical overview on ticagrelor in acute coronary syndromes

被引：15
作者：
Navarese, E. P. [1 ]
Buffon, A. [2 ]
Kozinski, M. [1 ]
Obonska, K. [1 ]
Rychter, M. [1 ]
Kunadian, V. [3 ]
Austin, D. [3 ]
De Servi, S. [4 ]
Sukiennik, A. [1 ]
Kubica, J. [1 ]
机构：
[1] Nicolaus Copernicus Univ, Coll Med, Dept Cardiol & Internal Med, PL-85094 Bydgoszcz, Poland
[2] Univ Cattolica Sacro Cuore, Dept Cardiol, I-800168 Rome, Italy
[3] Newcastle Tyne Hosp NHS Fdn Trust, Freeman Hosp, Ctr Cardiothorac, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
[4] Civ Hosp, Dept Cardiovasc Dis, I-20025 Legnano, Italy
来源：
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE | 2013年 / 106卷 / 02期
关键词：
PLATELET INHIBITION; TASK-FORCE; CLOPIDOGREL; PLATO; ASSOCIATION; REVASCULARIZATION; CONTRACTION; VARIABILITY; ANTAGONIST; MANAGEMENT;
D O I：
10.1093/qjmed/hcs187
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Until a few years ago, the mainstay of anti-platelet therapy in patients with acute coronary syndrome (ACS) was the combination of aspirin and clopidogrel, a P2Y12 receptor inhibitor. However, current clinical practice has now changed with the introduction of ticagrelor, a more potent cardiovascular drug than clopidogrel, without the limitations related to clopidogrel therapy. In this review, we provide a critical overview of ticagrelor in ACS, highlight the results with ticagrelor in several subgroups of patients and discuss the future trials.
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收藏
页码：105 / 115
页数：11
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