Electrospun polycaprolactone scaffolds for tissue engineering: a review

被引:95
作者
Janmohammadi, M. [1 ]
Nourbakhsh, M. S. [2 ]
机构
[1] Semnan Univ, Fac New Sci & Technol, Biomed Engn Biomat, Semnan, Iran
[2] Semnan Univ, Fac Mat & Met Engn, Biomed Engn Biomat, Semnan, Iran
关键词
Electrospinning; nanofibrous scaffolds; polycaprolactone; tissue engineering; NANOFIBROUS SCAFFOLDS; POLY(EPSILON-CAPROLACTONE); MINERALIZATION; CELLS; DIFFERENTIATION; DEGRADATION; MACROPHAGES; FABRICATION; COMPOSITES; PHOSPHATE;
D O I
10.1080/00914037.2018.1466139
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Polycaprolactone is a biodegradable and biocompatible polyester which has a wide range of applications in tissue engineering. Electrospinning, the versatile technique, used for the fabrication of fibrous scaffolds, which is widely used in tissue engineering, due to the ability of fabrication of nano/micro-scale fiber scaffolds. Polycaprolactone nanofiber scaffolds are widely used in tissue engineering and drug delivery. Polycaprolactone can be used in a wide variety of scaffolds construction. In this review, we will discuss the recent advances in the electrospinning of polycaprolactone nanofiber scaffolds in bone, cardiovascular, nerve, and skin tissue engineering. [GRAPHICS] .
引用
收藏
页码:527 / 539
页数:13
相关论文
共 72 条
[31]   Regenerative implants for cardiovascular tissue engineering [J].
Lee, Avione Y. ;
Mahler, Nathan ;
Best, Cameron ;
Lee, Yong-Ung ;
Breuer, Christopher K. .
TRANSLATIONAL RESEARCH, 2014, 163 (04) :321-341
[32]   Electrospinning of polysaccharides for regenerative medicine [J].
Lee, Kuen Yong ;
Jeong, Lim ;
Kang, Yun Ok ;
Lee, Seung Jin ;
Park, Won Ho .
ADVANCED DRUG DELIVERY REVIEWS, 2009, 61 (12) :1020-1032
[33]   Biomedical applications of nanofibers [J].
Leung, Victor ;
Ko, Frank .
POLYMERS FOR ADVANCED TECHNOLOGIES, 2011, 22 (03) :350-365
[34]   Biological response of chondrocytes cultured in three-dimensional nanofibrous poly(ε-caprolactone) scaffolds [J].
Li, WJ ;
Danielson, KG ;
Alexander, PG ;
Tuan, RS .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2003, 67A (04) :1105-1114
[35]  
Li Z., 2013, ONE DIMENSIONAL NANO, P15, DOI 10.1007/978-3-642-36427-3_2
[36]   Preparation and characterization of mesoporous bioactive glass/polycaprolactone nanofibrous matrix for bone tissues engineering [J].
Lin, Hsiu-Mei ;
Lin, Yi-Hsuan ;
Hsu, Fu-Yin .
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2012, 23 (11) :2619-2630
[37]   Bi-Layer Scaffold of Chitosan/PCL-Nanofibrous Mat and PLLA-Microporous Disc for Skin Tissue Engineering [J].
Lou, Tao ;
Leung, Matthew ;
Wang, Xuejun ;
Chang, Julia Yu Fong ;
Tsao, Ching Ting ;
Sham, Jonathan Ghing Chi ;
Edmondson, Dennis ;
Zhang, Miqin .
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2014, 10 (06) :1105-1113
[38]   Potential of nanofiber matrix as tissue-engineering scaffolds [J].
Ma, ZW ;
Kotaki, M ;
Inai, R ;
Ramakrishna, S .
TISSUE ENGINEERING, 2005, 11 (1-2) :101-109
[39]   Fabrication and evaluation of (PVA/HAp/PCL) bilayer composites as potential scaffolds for bone tissue regeneration application [J].
Maheshwari, Subramanian Uma ;
Samuel, Vasanth Kumar ;
Nagiah, Naveen .
CERAMICS INTERNATIONAL, 2014, 40 (06) :8469-8477
[40]   Tissue-engineered skin substitutes in regenerative medicine [J].
Mansbridge, Jonathan N. .
CURRENT OPINION IN BIOTECHNOLOGY, 2009, 20 (05) :563-567