Inhibition of hepatitis B virus gene expression: A step towards functional cure

被引：1
作者：
Zoulim, Fabien [1 ]
机构：
[1] Lyon Univ, Hosp Civils Lyon, Hepatol Dept, INSERM,U1052,Canc Res Ctr Lyon, 151 Cours Albert Thomas, F-69003 Lyon, France
来源：
JOURNAL OF HEPATOLOGY | 2018年 / 68卷 / 03期
关键词：
DEGRADATION;
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：386 / 388
页数：3
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  • [1] Safety and efficacy of REP 2139 and pegylated interferon alfa-2a for treatment-naive patients with chronic hepatitis B virus and hepatitis D virus co-infection (REP 301 and REP 301-LTF): a non-randomised, open-label, phase 2 trial
    Bazinet, Michel
    Pantea, Victor
    Cebotarescu, Valentin
    Cojuhari, Lilia
    Jimbei, Pavlina
    Albrecht, Jeffrey
    Schmid, Peter
    Le Gal, Frederic
    Gordien, Emmanuel
    Krawczyk, Adalbert
    Mijocevic, Hrvoje
    Karimzadeh, Hadi
    Roggendorf, Michael
    Vaillant, Andrew
    [J]. LANCET GASTROENTEROLOGY & HEPATOLOGY, 2017, 2 (12): : 877 - 889
  • [2] Adaptive immunity in HBV infection
    Bertoletti, Antonio
    Ferrari, Carlo
    [J]. JOURNAL OF HEPATOLOGY, 2016, 64 : S71 - S83
  • [3] In vivo reduction of hepatitis B virus antigenemia and viremia by antisense oligonucleotides
    Billioud, Gaetan
    Kruse, Robert L.
    Carrillo, Melissa
    Whitten-Bauer, Christina
    Gao, Dacao
    Kim, Aneeza
    Chen, Leon
    McCaleb, Michael L.
    Crosby, Jeffrey R.
    Hamatake, Robert
    Hong, Zhi
    Garaigorta, Urtzi
    Swayze, Eric
    Bissig, Karl-Dimiter
    Wieland, Stefan
    [J]. JOURNAL OF HEPATOLOGY, 2016, 64 (04) : 781 - 789
  • [4] The oral toll-like receptor-7 agonist GS-9620 in patients with chronic hepatitis B virus infection
    Gane, Edward J.
    Lim, Young-Suk
    Gordon, Stuart C.
    Visvanathan, Kumar
    Sicard, Eric
    Fedorak, Richard N.
    Roberts, Stuart
    Massetto, Benedetta
    Ye, Zhishen
    Pflanz, Stefan
    Garrison, Kimberly L.
    Gaggar, Anuj
    Subramanian, G. Mani
    McHutchison, John G.
    Kottilil, Shyamasundaran
    Freilich, Bradley
    Coffin, Carla S.
    Cheng, Wendy
    Kim, Yoon Jun
    [J]. JOURNAL OF HEPATOLOGY, 2015, 63 (02) : 320 - 328
  • [5] Synthetic RNAi triggers and their use in chronic hepatitis B therapies with curative intent
    Gish, Robert G.
    Yuen, Man-Fung
    Chan, Henry Lik Yuen
    Given, Bruce D.
    Lai, Ching-Lung
    Locarnini, Stephen A.
    Lau, Johnson Y. N.
    Wooddell, Christine I.
    Schluep, Thomas
    Lewis, David L.
    [J]. ANTIVIRAL RESEARCH, 2015, 121 : 97 - 108
  • [6] Intrahepatic innate immune response pathways are downregulated in untreated chronic hepatitis B
    Lebosse, Fanny
    Testoni, Barbara
    Fresquet, Judith
    Facchetti, Floriana
    Galmozzi, Enrico
    Fournier, Maelenn
    Hervieu, Valerie
    Berthillon, Pascale
    Berby, Francoise
    Bordes, Isabelle
    Durantel, David
    Levrero, Massimo
    Lampertico, Pietro
    Zoulim, Fabien
    [J]. JOURNAL OF HEPATOLOGY, 2017, 66 (05) : 897 - 909
  • [7] HBV cure: why, how, when?
    Levrero, Massimo
    Testoni, Barbara
    Zoulim, Fabien
    [J]. CURRENT OPINION IN VIROLOGY, 2016, 18 : 135 - 143
  • [8] Lok AS, 2017, HEPATOLOGY, V66, P1296, DOI [10.1002/hep.29323, 10.1016/j.jhep.2017.05.008]
  • [9] Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA
    Lucifora, Julie
    Xia, Yuchen
    Reisinger, Florian
    Zhang, Ke
    Stadler, Daniela
    Cheng, Xiaoming
    Sprinzl, Martin F.
    Koppensteiner, Herwig
    Makowska, Zuzanna
    Volz, Tassilo
    Remouchamps, Caroline
    Chou, Wen-Min
    Thasler, Wolfgang E.
    Hueser, Norbert
    Durantel, David
    Liang, T. Jake
    Muenk, Carsten
    Heim, Markus H.
    Browning, Jeffrey L.
    Dejardin, Emmanuel
    Dandri, Maura
    Schindler, Michael
    Heikenwalder, Mathias
    Protzer, Ulrike
    [J]. SCIENCE, 2014, 343 (6176) : 1221 - 1228
  • [10] Mueller H, 2018, J HEPATOL, V68, P412, DOI 10.1016/j.jhep.2017.10.014
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