Relation Between Monocyte to High-Density Lipoprotein Cholesterol Ratio With Presence and Severity of Isolated Coronary Artery Ectasia

被引：85
作者：
Kundi, Harun [1 ]
Gok, Murat [1 ]
Kiziltunc, Emrullah [1 ]
Cetin, Mustafa [1 ]
Cicekcioglu, Hulya [1 ]
Cetin, Zebra Guven [1 ]
Karayigit, Orhan [1 ]
Ornek, Ender [1 ]
机构：
[1] Ankara Numune Training & Res Hosp, Dept Cardiol, Ankara, Turkey
来源：
AMERICAN JOURNAL OF CARDIOLOGY | 2015年 / 116卷 / 11期
关键词：
ENDOTHELIAL-CELLS; DISEASE; MECHANISMS; HDL;
D O I：
10.1016/j.amjcard.2015.08.036
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The aim of this study was to investigate an easily available inflammatory and oxidative stress marker and monocyte to high-density lipoprotein cholesterol ratio (MHR) in patients with coronary artery ectasia (CAE). The study population included 405 patients of which 135 patients had isolated CAE, 135 patients had obstructive coronary artery disease (CAD), and 135 patients had normal coronary angiograms (NCAs). The severity of isolated CAE was determined according to the Markis classification. The MHR was significantly greater in patients with isolated CAE than those with obstructive CAD and NCAs: 14.8 (11.6 to 19.8), 11.4 (9.6 to 13.5), 9.8 (7.5 to 11.9), respectively. Linear regression analyses showed that MHR and C-reactive protein were significantly related with the severity of isolated CAE. In conclusion, the MHR is significantly greater in patients with CAE compared to controls with obstructive CAD and NCAs, and MHR is associated with the severity of CAE. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码：1685 / 1689
页数：5
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