Multi-walled carbon nanotube based multi-electrode arrays for the detection of the emergent activity in the cortical network

被引：5
作者：
Martin-Fernandez, Inigo [1 ]
Gabriel, Gemma [1 ,2 ]
Guimera, Anton [1 ,2 ]
Palomer, Xavier [3 ]
Reig, Ramon [3 ]
Sanchez-Vives, Maria V. [3 ]
Villa, Rosa [1 ,2 ,4 ]
Godignon, Philippe [1 ,2 ]
机构：
[1] CSIC, Inst Microelect Barcelona IMB CNM, Barcelona 08193, Spain
[2] CIBER BBN, Networking Ctr Bioengn Biomat & Nanomed, Barcelona, Spain
[3] IDIBAPS Inst Biomed Res August Pi i Sunyer, Barcelona, Spain
[4] ICREA, Barcelona, Spain
来源：
MICROELECTRONIC ENGINEERING | 2013年 / 112卷
关键词：
Carbon nanotubes; Multi electrode array system; Integration; Electrical impedance spectroscopy; Cyclic voltammetry; Neural recording; MICROELECTRODES; PURIFICATION; ELECTRODES; DISPERSION;
D O I：
10.1016/j.mee.2013.05.009
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
We present a novel carbon nanotube growth method for the selective growth of high density arrays of multi walled carbon nanotubes (MWCNT) on multi electrode arrays systems (MEA). Platinum (Pt) has been used as the electrode material but also as the metal to catalyse the growth of the MWCNTs. These MWCNTs modified electrodes present a lower impedance compared to the original electrodes and thus, enhance the electrode sensitivity, increase its electric charge transfer and also improve the electrode-tissue contact. The system was tested for the recording of spontaneous rhythmic activity generated by ferret cortical slices before and after blockade of inhibition. (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码：14 / 20
页数：7
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