Subcutaneous Panniculitis-Like T-Cell Lymphoma in Two Pediatric Patients: An HIV-Positive Adolescent and a 4-Month-Old Infant

被引：8

作者：

Acree, Sara C. ^{[1
]}

Tovar, Jason P. ^{[2
]}

Pattengale, Paul K. ^{[2
]}

Wang, Larry L. ^{[2
]}

Church, Joseph A. ^{[3
,4
]}

Gaynon, Paul S. ^{[4
,5
]}

Cassarino, David S. ^{[6
]}

机构：

[1] LAC USC Med Ctr, Dept Pathol, Los Angeles, CA USA

[2] Childrens Hosp Los Angeles, Dept Pathol, Los Angeles, CA 90027 USA

[3] USC, Childrens Hosp Los Angeles, Dept Pediat, Div Clin Immunol & Allergy, Los Angeles, CA USA

[4] USC, Keck Sch Med, Los Angeles, CA USA

[5] USC, Childrens Hosp Los Angeles, Dept Pediat, Div Hematol Oncol, Los Angeles, CA USA

[6] So Calif Permanente Med Grp, Dept Pathol, Los Angeles, CA 90027 USA

来源：

FETAL AND PEDIATRIC PATHOLOGY | 2013年 / 32卷 / 03期

关键词：

subcutaneous panniculitis-like T-cell lymphoma (SPTCL); SPTCL and pediatrics; SPTCL and children; SPTCL and HIV; PROGNOSTIC-FACTORS; CLASSIFICATION;

D O I：

10.3109/15513815.2012.701264

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Subcutaneous Panniculitis-like T-cell lymphoma (SPTCL) is a rare subtype of childhood non-Hodgkin lymphoma. Subcutaneous Panniculitis-like T-cell lymphoma has an aggressive variant associated with the hemophagocytic syndrome (HPS). Patients without HPS show resolution of the disease with prednisone or immunosuppressive therapy unlike other T-cell lymphomas. One HIV-positive adolescent and one infant with multiple subcutaneous masses are presented and the literature is reviewed. Lesional cells were consistent with SPTCL alpha-beta type. Our cases, without HPS, showed complete resolution of their lesions when treated with non-aggressive therapies. Patients with SPTCL alpha-beta should be treated conservatively.

引用

页码：175 / 183

页数：9

共 17 条

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