Imaging non motor signs in Parkinson's disease

被引：0
作者：
Thobois, S. [1 ,2 ,3 ]
Ballanger, B. [1 ]
Poisson, A. [1 ,2 ,3 ]
Broussolle, E. [1 ,2 ,3 ]
机构：
[1] Ctr Neurosci Cognit, CNRS, UMR 5229, F-69675 Bron, France
[2] Hop Neurol & Neurochirurg P Wertheimer, Hosp Civils Lyon, F-69677 Bron, France
[3] Univ Lyon, Fac Med & Maieut Lyon Sud Charles Merieux, F-69921 Oullins, France
来源：
REVUE NEUROLOGIQUE | 2012年 / 168卷 / 8-9期
关键词：
Parkinson; Pathophysiology; Functional imaging; Non-motor manifestations; SUBTHALAMIC NUCLEUS STIMULATION; DEEP-BRAIN-STIMULATION; CORTICAL CHOLINERGIC DENERVATION; CEREBRAL GLUCOSE-METABOLISM; QUALITY-OF-LIFE; DOPAMINERGIC MODULATION; COGNITIVE IMPAIRMENT; OLFACTORY DYSFUNCTION; DEPRESSIVE SYMPTOMS; ANTERIOR CINGULATE;
D O I：
10.1016/j.neurol.2012.05.007
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Parkinson's disease is mainly considered as a motor disorder defined by a motor triad. However, various non-motor manifestations may be encountered in Parkinson's disease, including hyposmia, pain, fatigue, sleep disorders, cognitive and behavioral disorders. The pathophysiology of these signs is complex, not univocal and remains poorly understood. Functional imaging techniques either by positron emission tomography, single photon emission tomography or functional magnetic resonance imaging provide an invaluable opportunity to better understand the pathophysiology of these signs. In this paper, we present a review of the recent advances provided by functional imaging in this area. (C) 2012 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：576 / 584
页数：9
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