Role of the National Poliovirus Laboratory for the Program of Eradication and Poliomyelitis Surveillance

被引:3
作者
Trallero, Gloria [1 ]
Cabrerizo, Maria [1 ]
Avellon, Ana [1 ]
机构
[1] Inst Salud Carlos III, Ctr Nacl Microbiol, Lab Nacl Poliovirus, Madrid, Spain
来源
REVISTA ESPANOLA DE SALUD PUBLICA | 2013年 / 87卷 / 05期
关键词
Poliovirus; Poliomyelitis; Disease eradication; Poliovirus vaccine; oral; inactivated; Health planning; Public health surveillance; ENTEROVIRUSES; PARALYSIS; SPAIN;
D O I
10.4321/S1135-57272013000500006
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The Spanish acute flaccid paralysis surveillance network is coordinated by the National Poliovirus Laboratory (NPL), which, since 1998, carries out polioviruses (PV) and other enteroviruses detected characterization by cell culture and molecular techniques. A total of 110,725 (70046+40679) samples were studied between 1998-2012 and enteroviruses were detected in 8% of these. Among these enteroviruses 241 PV were characterized as PV Sabin-like, except samples belong to an imported poliomyelitis case, all of which were characterised as vaccine derived PV type 2. The NPL has carried out the serotyping and the intratypic differentation of all the isolated PV in Spain of any syndrome. It is shown that wild PV has not circulated in our country during the 15 years studied and that has led to the signing of the Act of the "eradication of poliomyelitis in Spain" by WHO in 2001, and the "certification of the eradication of wild PV free for European countries on 21 June 2002. Currently only 3 countries have endemic transmission of wild PV (Pakistan, Afghanistan and Nigeria). Until a complete worldwide eradication, was achieved, Spain will actively continue to participate in the maintenance of the poliomyelitis eradication infrastructure by monitoring and vaccination as well as the wild PV containment plan to avoid the spread of wild PV.
引用
收藏
页码:471 / 479
页数:9
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