Kip1 meets SKP2: new links in cell-cycle control

被引:51
作者
Amati, B [1 ]
Vlach, J [1 ]
机构
[1] Swiss Inst Expt Canc Res, CH-1066 Epalinges, Switzerland
关键词
D O I
10.1038/12087
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The cyclin-dependent kinase inhibitor p27(Kip1) degraded in a phosphorylation- and ubiquitin-dependent way upon cell-cycle entry. p45(SKP2), the adaptor subunit of the ubiquitin-protein ligase SCFSKP2, may mediate recognition and ubiquitination or phosphorylated p27(Kip1).
引用
收藏
页码:E91 / E93
页数:3
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