Synchrotron X-ray diffraction study of the structure of oral stratum corneum model lipid membranes

被引:0
|
作者
Ryabova, N. Yu. [1 ,2 ]
Gruzinov, A. Yu. [3 ]
Zabelin, A. V. [3 ]
机构
[1] Joint Inst Nucl Res, Dubna 141980, Moscow Oblast, Russia
[2] Moscow MV Lomonosov State Univ, Skobeltsyn Inst Nucl Phys, Moscow 119234, Russia
[3] Natl Res Ctr, Kurchatov Inst, Moscow 123182, Russia
基金
俄罗斯基础研究基金会;
关键词
PHASE-BEHAVIOR; NEUTRON-DIFFRACTION; FATTY-ACIDS; ORGANIZATION; CHOLESTEROL; MIXTURE; SKIN;
D O I
10.1134/S106377451401012X
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
Membranes modeling the lipid fraction of the mucous membrane of the human oral cavity have been studied by X-ray synchrotron diffraction. Ternary systems, composed of a mixture of sphingomyelin, dipalmitoylphosphatidylcholine, and dipalmitoylphosphatidylethanolamine with component weight ratios of 1: 2: 2 and 1: 2: 1, have lamellar structures in the gel phase at the physiological temperature (37A degrees C). An inverted hexagonal phase is formed in the system with 40% dipalmitoylphosphatidylethanolamine in the temperature range of 60-70A degrees C. This phase coexists with the liquid-crystalline lamellar phase in a narrow temperature range and completely surpresses the lamellar phase with an increase in temperature to 80A degrees C. Multi-component oral stratum corneum membranes are characterized by several lamellar phases at 20-37A degrees C and the coexistence of one or several lamellar phases with inverted hexagonal phase at 80-90A degrees C.
引用
收藏
页码:117 / 124
页数:8
相关论文
共 50 条
  • [1] Synchrotron X-ray diffraction study of the structure of oral stratum corneum model lipid membranes
    N. Yu. Ryabova
    A. Yu. Gruzinov
    A. V. Zabelin
    Crystallography Reports, 2014, 59 : 117 - 124
  • [2] Microbeam X-ray diffraction study of lipid structure in stratum corneum of human skin
    Yagi, Naoto
    Aoyama, Koki
    Ohta, Noboru
    PLOS ONE, 2020, 15 (05):
  • [3] Neutron diffraction studies of oral stratum corneum model lipid membranes
    Natalia Yu Ryabova
    Stanislav G. Sheverev
    Thomas Hauß
    European Biophysics Journal, 2013, 42 : 621 - 629
  • [4] Neutron diffraction studies of oral stratum corneum model lipid membranes
    Ryabova, Natalia Yu
    Sheverev, Stanislav G.
    Hauss, Thomas
    EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2013, 42 (08): : 621 - 629
  • [5] Stratum Corneum Function: A Structural Study with Dynamic Synchrotron X-ray Diffraction Experiments
    Hatta, Ichiro
    Nakazawa, Hiromitsu
    Ohta, Noboru
    Uchino, Tomonobu
    Yanase, Kaori
    JOURNAL OF OLEO SCIENCE, 2021, 70 (09) : 1181 - 1199
  • [6] Evaluation of the molecular lipid organization in millimeter-sized stratum corneum by synchrotron X-ray diffraction
    Suzuki, T.
    Uchino, T.
    Hatta, I
    Miyazaki, Y.
    Kato, S.
    Sasaki, K.
    Kagawa, Y.
    SKIN RESEARCH AND TECHNOLOGY, 2018, 24 (04) : 621 - 629
  • [7] Effect of iontophoresis in combination with ionic enhancers on the lipid structure of the stratum corneum: An x-ray diffraction study
    Chesnoy, S
    Doucet, J
    Durand, D
    Couarraze, G
    PHARMACEUTICAL RESEARCH, 1996, 13 (10) : 1581 - 1584
  • [8] X-Ray diffraction study on ordered, disordered and reconstituted intercellular lipid lamellar structure in stratum corneum
    Hatta, I
    Ohta, N
    Ban, S
    Tanaka, H
    Nakata, S
    BIOPHYSICAL CHEMISTRY, 2001, 89 (2-3) : 239 - 242
  • [9] STUDY OF LIPID AND NONLIPID STRUCTURE IN HUMAN STRATUM-CORNEUM BY X-RAY-DIFFRACTION
    GARSON, JC
    DOUCET, J
    TSOUCARIS, G
    LEVEQUE, JL
    JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS, 1990, 41 (06): : 347 - 358
  • [10] New Insights into the Stratum Corneum Lipid Organization by X-Ray Diffraction Analysis
    Groen, D.
    Gooris, G. S.
    Bouwstra, J. A.
    BIOPHYSICAL JOURNAL, 2009, 97 (08) : 2242 - 2249