Azobisisobutyronitrile Initiated Aerobic Oxidative Transformation of Amines: Coupling of Primary Amines and Cyanation of Tertiary Amines

被引：108
作者：
Liu, Lianghui [1 ]
Wang, Zikuan [1 ]
Fu, Xuefeng [1 ]
Yan, Chun-Hua [1 ]
机构：
[1] Peking Univ, Coll Chem & Mol Engn, State Key Lab Rare Earth Mat Chem & Applicat, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China
来源：
ORGANIC LETTERS | 2012年 / 14卷 / 22期
基金：
美国国家科学基金会;
关键词：
N-HYDROXYPHTHALIMIDE NHPI; BAEYER-VILLIGER OXIDATION; PRIMARY ALIPHATIC-AMINES; CARBON BOND FORMATION; ONE-POT SYNTHESIS; METAL-FREE; CATALYTIC-SYSTEM; HYDROGEN-PEROXIDE; MOLECULAR-OXYGEN; SODIUM-CYANIDE;
D O I：
10.1021/ol302708r
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In the presence of a catalytic amount of radical initiator AIBN, primary amines are oxidatively coupled to imines and tertiary amines are cyanated to alpha-aminonitriles. These "metal-free" aerobic oxidative coupling reactions may find applications in a wide range of "green" oxidation chemistry.
引用
收藏
页码：5692 / 5695
页数：4
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