Human African Trypanosomiasis

被引：29

作者：

Brun, Reto ^{[1
]}

Blum, Johannes ^{[2
]}

机构：

[1] Swiss Trop & Publ Hlth Inst, Dept Med Parasitol & Infect Biol, CH-4002 Basel, Switzerland

[2] Swiss Trop & Publ Hlth Inst, Dept Med Serv & Diagnost, Outpatient Clin, CH-4002 Basel, Switzerland

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2012年 / 26卷 / 02期

关键词：

Human African trypanosomiasis; Sleeping sickness; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Epidemiology; Diagnosis; Treatment; CATT/TRYPANOSOMA-BRUCEI-GAMBIENSE; SLEEPING SICKNESS; DIAGNOSIS; SURVEILLANCE; EFLORNITHINE; MELARSOPROL; RHODESIENSE; TRIAL; STAGE; MRI;

D O I：

10.1016/j.idc.2012.03.003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Human African trypanosomiasis (sleeping sickness) is caused by the uni-cellular parasite Trypanosoma brucei and transmitted by tsetse flies. It occurs exclusively in sub-Saharan Africa, usually in rural areas affected by civil conflicts and neglected health systems. Reported cases are fewer than 10,000/year, which classifies it as one of the most neglected tropical diseases. Because sleeping sickness is fatal if not treated, it has to be included in the differential diagnosis of every febrile traveler returning from a game park in East Africa. Elimination of the disease is considered feasible provided better tools for diagnosis and treatment can be made available.

引用

页码：261 / +

页数：14

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