Clinical and Cognitive Correlates of Insight in Bipolar Disorder

被引：10

作者：

Camelo, Evelyn ^{[1
]}

Mograbi, Daniel C. ^{[8
,9
]}

da Silva, Rafael de Assis ^{[1
,10
]}

Santana, Cristina M. T. ^{[1
,9
]}

Ferreira do Nascimento, Rodrigo L. ^{[9
]}

de Oliveira e Silva, Adriana Cardoso ^{[2
,3
,4
,5
]}

Nardi, Antonio Egidio ^{[6
,7
]}

Cheniaux, Elie ^{[1
,11
]}

机构：

[1] Univ Fed Rio de Janeiro, Rio De Janeiro, RJ, Brazil

[2] Univ Fed Rio de Janeiro, Fac Med, Rio De Janeiro, RJ, Brazil

[3] Univ Fed Rio de Janeiro, Grad Program Psychiat & Mental Hlth PROPSAM, Inst Psychiat IPUB, Rio De Janeiro, RJ, Brazil

[4] Univ Fed Rio de Janeiro, Pan & Respirat Lab, IPUB, Rio De Janeiro, RJ, Brazil

[5] Univ Fed Rio de Janeiro, Lab Thanatol, IPUB, Rio De Janeiro, RJ, Brazil

[6] Univ Fed Rio de Janeiro, Fac Med, Inst Psychiat, Psychiat, Rio De Janeiro, RJ, Brazil

[7] Univ Fed Rio de Janeiro, Lab Pan & Respirat, Inst Psychiat, Rio De Janeiro, RJ, Brazil

[8] Kings Coll London, Inst Psychiat Psychol & Neurosci, P078,De Crespigny Pk, London SE5 8AF, England

[9] Pontificia Univ Catololica Rio de Janeiro PUC Rio, Rio De Janeiro, RJ, Brazil

[10] Univ Fed Estado Rio de Janeiro UNIRIO, Rio De Janeiro, RJ, Brazil

[11] Univ Estado Rio de Janeiro, Rio De Janeiro, RJ, Brazil

来源：

PSYCHIATRIC QUARTERLY | 2019年 / 90卷 / 02期

关键词：

Insight; Cognition; Bipolar disorder; Awareness; RATING-SCALE; I DISORDER; ATTENTION; NEUROCOGNITION; VALIDITY; TRAIL;

D O I：

10.1007/s11126-019-09627-2

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Insight is greatly impaired in Bipolar Disorder (BD), especially during mania. Cognitive impairment is also present in BD. Despite that, few studies have investigated a possible association between these two aspects. The main goal of the current study is to compare BD affective states regarding performance in cognitive testing and investigate clinical and cognitive predictors for insight loss in BD. The study investigated a sample of 65 patients who were evaluated in one of the BD phases (mania, euthymia or depression). All the subjects underwent neuropsychological evaluation and completed the Insight Scale for Affective Disorders (ISAD). The relationship between level of insight and clinical/cognitive variables was analyzed through multiple regression models. No significant differences were found among BD phases regarding performance on cognitive testing. Insight was more impaired in mania then in depression or euthymia. Predictors for loss of insight were: severity of manic symptoms and impairments in selective attention (Symbol search test), divided attention (Trail making test) and inhibition (Stroop test). The sample size is a potential limitation of the current study. Nevertheless, the results suggest this had limited impact, with group differences being detected for a number of variables. The results found have important clinical importance, suggesting, for example, that rehabilitation of specific cognitive skills may improve insight in BD.

引用

页码：385 / 394

页数：10

共 35 条

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