Historical Perspectives and Recent Research on DNA Hydrogel-Based Stimuli-Responsive Systems and Bioengineering Applications

被引：4

作者：

Cao, Zhifu ^{[1
]}

Li, Kai ^{[2
]}

Wang, Chong ^{[3
]}

Liu, Jia ^{[1
]}

Tang, Yujin ^{[1
]}

Wang, Liqiang ^{[1
,4
]}

机构：

[1] Youjiang Med Univ Nationalities, Affiliated Hosp, Guangxi Biomed Mat Engn Res Ctr Bone & Joint Dege, Dept Orthopaed,Guangxi Key Lab Basic & Translat R, Baise 533000, Guangxi, Peoples R China

[2] Southern Med Univ, Affiliated Hosp 3, Acad Orthoped, Guangdong Prov Key Laboratoryof Bone & Joint Dege, Guangzhou 510663, Guangdong, Peoples R China

[3] Dongguan Univ Technol, Sch Mech Engn, Dongguan 523820, Guangdong, Peoples R China

[4] Shanghai Jiao Tong Univ, Sch Mat Sci & Engn, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R China

来源：

ACS APPLIED POLYMER MATERIALS | 2022年 / 5卷 / 01期

基金：

中国国家自然科学基金;

关键词：

artificial extracellular matrix; bioengineering; DNA; hydrogels; stimuli-responsive; BIOMEDICAL APPLICATIONS; NUCLEIC-ACIDS; TUMOR-CELLS; I-MOTIF; HYBRIDIZATION; NANOSTRUCTURES; NANOTECHNOLOGY; DELIVERY; PLATFORM; RELEASE;

D O I：

10.1021/acsapm.2c01528

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Soft hydrogel materials have attracted increasing attention from scientists due to the programmability of nucleic acids. DNA hydrogels are increasingly used in biomedicine due to their natural biocompatibiity and degradation properties. Moreover, the addition of various molecules to these hydrogels can enhance the superiority and utility of DNA hydrogels. Therefore, the present study aimed to provide a timely overview of historical perspectives and recent research advances in DNA hydrogels and their applications in bioengineering and stimulus-responsive systems. The state-of-the-art problems and future prospects of DNA hydrogels were also discussed.

引用

页码：31 / 49

页数：19

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