Chromatographic properties in normal-mode HPLC of chiral stationary phases based on substituted beta-cyclodextrins

被引：16

作者：

Cachau, C ^{[1
]}

Thienpont, A ^{[1
]}

Soulard, MH ^{[1
]}

Felix, G ^{[1
]}

机构：

[1] ENSCPB,CNRS,URA 35,F-33402 TALENCE,FRANCE

来源：

CHROMATOGRAPHIA | 1997年 / 44卷 / 7-8期

关键词：

column liquid chromatography; chiral stationary phases; bonded substituted cyclodextrins; normal mode separations;

D O I：

10.1007/BF02466319

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Substituted beta-cyclodextrin chiral stationary phases having different types of phenyl carbamate substituents have been prepared and evaluated (retention, selectivity, resolution) for the liquid chromatographic separation of several series of enantiomers. The influence on separations of the degree of substitution and the structure of the substituent are discussed. Different mechanisms are suggested to explain separations in normal mode conditions.

引用

页码：411 / 416

页数：6

共 14 条

[1]

Allenmark StigG., 1988, CHROMATOGRAPHIC ENAN

[2]

AMSTRONG DW, 1982, ANAL CHEM, V62, P1610

[3]

DALGLIESH CE, 1952, J CHEM SOC, V137, P3940

[4]

FELIX G, 1993, HRC-J HIGH RES CHROM, V16, P364