DigSee: disease gene search engine with evidence sentences (version cancer)

被引：99

作者：

Kim, Jeongkyun ^{[1
]}

So, Seongeun ^{[1
]}

Lee, Hee-Jin ^{[2
]}

Park, Jong C. ^{[2
]}

Kim, Jung-jae ^{[3
]}

Lee, Hyunju ^{[1
]}

机构：

[1] Gwangju Inst Sci & Technol, Sch Informat & Commun, Buk Go 500712, Gwangju, South Korea

[2] Korea Adv Inst Sci & Technol, Dept Comp Sci, Taejon 305701, South Korea

[3] Nanyang Technol Univ, Sch Comp Engn, Singapore 639798, Singapore

来源：

NUCLEIC ACIDS RESEARCH | 2013年 / 41卷 / W1期

基金：

新加坡国家研究基金会;

关键词：

DRAGON DATABASE; EXPRESSION; TOOL; PHOSPHORYLATION; PRIORITIZATION; LOCALIZATION; METHYLATION; MUTATIONS; PROTEINS;

D O I：

10.1093/nar/gkt531

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Biological events such as gene expression, regulation, phosphorylation, localization and protein catabolism play important roles in the development of diseases. Understanding the association between diseases and genes can be enhanced with the identification of involved biological events in this association. Although biological knowledge has been accumulated in several databases and can be accessed through the Web, there is no specialized Web tool yet allowing for a query into the relationship among diseases, genes and biological events. For this task, we developed DigSee to search MEDLINE abstracts for evidence sentences describing that 'genes' are involved in the development of 'cancer' through 'biological events'. DigSee is available through http://gcancer.org/digsee.

引用

页码：W510 / W517

页数：8

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