Clinical Profile of Ulcerative Colitis Patients in a Tertiary Care Center: An Experience from Rural India

被引:0
作者
Soni, Amit [1 ]
机构
[1] Maharishi Markandeshwar Deemed Be Univ MMDU, Maharishi Markandeshwar Inst Med Sci & Res MMIMSR, Dept Gastroenterol, Ambala 133207, Haryana, India
基金
英国科研创新办公室;
关键词
Ulcerative colitis; Azathioprine; Colon; Extra-intestinal manifestations (EIM); INFLAMMATORY-BOWEL-DISEASE; PREVALENCE; SURGERY; HISTORY;
D O I
10.1007/s12262-020-02545-9
中图分类号
R61 [外科手术学];
学科分类号
摘要
Ulcerative colitis is a chronic idiopathic inflammatory condition of the colon, characterized by relapsing and remitting course. This study was done to look at the clinical profile of ulcerative colitis patients in a tertiary care hospital, located in rural area of northern India. All patients with ulcerative colitis and age above 18 years who attended outpatient clinics from November 2019 to January 2020 were included in the study. A total of 45 patients were included in the study. There were 19 males (42.22%) and mean age of the patients was 37.08 (+/- 11.58) years. The most common presenting complain was blood in stools (88.88%). The majority of the patients (62.22%) had pancolitis. Family history of proven IBD was found in 1 (2.22%) patient only. Extra-intestinal manifestations were seen in 7 patients (15.55%) commonest being arthralgia. Thirty-three patients (73.33%) were on oral mesalazine, 20 patients (44.44%) were on azathioprine, and 9 patients (20%) were on oral corticosteroids. None of the patients was on biologics. Slight female predominance, fewer EIM, less family history of IBD, higher percentage of pancolitis, and significant percentage of patients on oral immunosuppressant (azathioprine) are the key features observed in this study from rural India.
引用
收藏
页码:915 / 919
页数:5
相关论文
共 20 条
[1]   The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017 [J].
Alatab, Sudabeh ;
Sepanlou, Sadaf G. ;
Ikuta, Kevin ;
Vahedi, Homayoon ;
Bisignano, Catherine ;
Safiri, Saeid ;
Sadeghi, Anahita ;
Nixon, Molly R. ;
Abdoli, Amir ;
Abolhassani, Hassan ;
Alipour, Vahid ;
Almadi, Majid A. H. ;
Almasi-Hashiani, Amir ;
Anushiravani, Amir ;
Arabloo, Jalal ;
Atique, Suleman ;
Awasthi, Ashish ;
Badawi, Alaa ;
Baig, Atif A. A. ;
Bhala, Neeraj ;
Bijani, Ali ;
Biondi, Antonio ;
Borzi, Antonio M. ;
Burke, Kristin E. ;
Carvalho, Felix ;
Daryani, Ahmad ;
Dubey, Manisha ;
Eftekhari, Aziz ;
Fernandes, Eduarda ;
Fernandes, Joao C. ;
Fischer, Florian ;
Haj-Mirzaian, Arvin ;
Haj-Mirzaian, Arya ;
Hasanzadeh, Amir ;
Hashemian, Maryam ;
Hay, Simon, I ;
Hoang, Chi L. ;
Househ, Mowafa ;
Ilesanmi, Olayinka S. ;
Balalami, Nader Jafari ;
James, Spencer L. ;
Kengne, Andre P. ;
Malekzadeh, Masoud M. ;
Merat, Shahin ;
Meretoja, Tuomo J. ;
Mestrovic, Tomislav ;
Mirrakhimov, Erkin M. ;
Mirzaei, Hamed ;
Mohammad, Karzan A. ;
Mokdad, Ali H. .
LANCET GASTROENTEROLOGY & HEPATOLOGY, 2020, 5 (01) :17-30
[2]   Indications and Options for Surgery in Ulcerative Colitis [J].
Bohl, Jaime L. ;
Sobba, Kathryn .
SURGICAL CLINICS OF NORTH AMERICA, 2015, 95 (06) :1211-+
[3]  
Cha JM, 2019, GUT, Vii
[4]   Ulcerative colitis in south India [J].
Cherian, Jijo V. ;
Muthusamy, Arun Kumar ;
Navaneetham, Udhay ;
Venkatakrishnan, Jayanthi ;
Malathi, S. Malathi .
GASTROINTESTINAL ENDOSCOPY, 2007, 65 (05) :AB270-AB270
[5]   A comprehensive review and update on ulcerative colitis [J].
Gajendran, Mahesh ;
Loganathan, Priyadarshini ;
Jimenez, Guillermo ;
Catinella, Anthony P. ;
Ng, Nathaniel ;
Umapathy, Chandraprakash ;
Ziade, Nathalie ;
Hashash, Jana G. .
DM DISEASE-A-MONTH, 2019, 65 (12)
[6]   Regular review - Ulcerative colitis [J].
Ghosh, S ;
Shand, A ;
Ferguson, A .
BMJ-BRITISH MEDICAL JOURNAL, 2000, 320 (7242) :1119-1123
[7]  
Gunisetty S, 2012, O J IMMUNOL, V2, P144, DOI [10.4236/oji.2012.24018, DOI 10.4236/OJI.2012.24018]
[8]   Prevalence and Characteristics of Extra-intestinal Manifestations in a Large Cohort of Greek Patients with Inflammatory Bowel Disease [J].
Karmiris, Konstantinos ;
Avgerinos, Anastasios ;
Tavernaraki, Aikaterini ;
Zeglinas, Christos ;
Karatzas, Pantelis ;
Koukouratos, Theodoros ;
Oikonomou, Konstantinos A. ;
Kostas, Athanasios ;
Zampeli, Evanthia ;
Papadopoulos, Vasileios ;
Theodoropoulou, Angeliki ;
Viazis, Nikos ;
Polymeros, Dimitrios ;
Michopoulos, Spyridon ;
Bamias, Giorgos ;
Kapsoritakis, Andreas ;
Karamanolis, Dimitrios G. ;
Mantzaris, Gerassimos J. ;
Tzathas, Charalampos ;
Koutroubakis, Ioannis E. .
JOURNAL OF CROHNS & COLITIS, 2016, 10 (04) :429-436
[9]  
Kedia S, 2018, INDIAN J GASTROENTER, V37, P183, DOI 10.1007/s12664-018-0852-y
[10]   Surgical Principles in the Treatment of Ulcerative Colitis [J].
Kuehn, Florian ;
Klar, Ernst .
VISZERALMEDIZIN, 2015, 31 (04) :246-250