The role of dyslipidemia and statins in venous thromboembolism

被引:35
作者
Ray, JG [1 ]
Rosendaal, FR
机构
[1] Univ Toronto, Dept Med, Toronto, ON, Canada
[2] McMaster Univ, Dept Clin Epidemiol & Biostat, Hamilton, ON, Canada
[3] Leiden Univ, Med Ctr, Ctr Hemostasis & Thrombosis Res, Leiden, Netherlands
[4] Leiden Univ, Med Ctr, Dept Clin Epidemiol, Leiden, Netherlands
来源
CURRENT CONTROLLED TRIALS IN CARDIOVASCULAR MEDICINE | 2001年 / 2卷 / 04期
关键词
deep vein thrombosis; HMG CoA reductase inhibitors; hyperlipidemia; lipids; statins; venous thromboembolism;
D O I
10.1186/CVM-2-4-165
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Recent studies have proposed an association between hyperlipidemia and venous thromboembolism (VTE). We review the epidemiological evidence linking dyslipidemia with VTE and examine several possible underlying mechanisms. We discuss the possible role of HMG CoA reductase inhibitors (statins) in the prevention and treatment of VTE and suggest future directions for research.
引用
收藏
页码:165 / 170
页数:6
相关论文
共 58 条
  • [1] The effect of aggressive and moderate lowering of LDL-cholesterol and low dose anticoagulation on plasma lipids, apolipoproteins and lipoprotein families in post coronary artery bypass graft trial
    Alaupovic, P
    Fesmire, JD
    Hunnighake, D
    Domanski, M
    Forman, S
    Knatterud, GL
    Forrester, J
    Herd, JA
    Hoogwerf, B
    Campeau, L
    Gobel, FL
    [J]. ATHEROSCLEROSIS, 1999, 146 (02) : 369 - 379
  • [2] Ambrosi P, 2000, THROMB HAEMOSTASIS, V83, P46
  • [3] Amerongen GPV, 2000, CIRCULATION, V102, P2803
  • [4] [Anonymous], 2000, Hematology basic principles and practice
  • [5] Atsumi T, 1998, J RHEUMATOL, V25, P69
  • [6] Do triglycerides provide meaningful information about heart disease risk?
    Avins, AL
    Neuhaus, JM
    [J]. ARCHIVES OF INTERNAL MEDICINE, 2000, 160 (13) : 1937 - 1944
  • [7] Antiphospholipid syndrome and thrombosis
    Bick, RL
    Baker, WF
    [J]. SEMINARS IN THROMBOSIS AND HEMOSTASIS, 1999, 25 (03) : 333 - 350
  • [8] BLADBJERG EM, 1994, THROMB HAEMOSTASIS, V71, P755
  • [9] BLAKE GJ, 2000, CURR CONTR TRIALS C, V1, P131
  • [10] A QUANTITATIVE ASSESSMENT OF PLASMA HOMOCYSTEINE AS A RISK FACTOR FOR VASCULAR-DISEASE - PROBABLE BENEFITS OF INCREASING FOLIC-ACID INTAKES
    BOUSHEY, CJ
    BERESFORD, SAA
    OMENN, GS
    MOTULSKY, AG
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1995, 274 (13): : 1049 - 1057