B regulatory cells in cancer

被引:99
作者
Balkwill, Frances [1 ]
Montfort, Anne [1 ]
Capasso, Melanie [1 ]
机构
[1] Queen Mary Univ London, Barts Canc Inst, Ctr Canc & Inflammat, London EC1M 6BQ, England
关键词
B cells; B regulatory cells; interleukin-10; cancer; anti-CD20; immunosuppression; T-CELLS; CD20; IMMUNOTHERAPY; LYMPHOMA DEPLETION; B10; CELLS; MICE; IL-10; LYMPHOCYTES; SUBSET; TUMORS; AUTOIMMUNITY;
D O I
10.1016/j.it.2012.10.007
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
B regulatory cells are a newly described subpopulation of B cells that appear to play important roles in autoimmunity and more recently, in cancer. In this review we summarize our current knowledge of B regulatory cells, as well as the body of evidence pointing towards a role for B cells in general, and B regulatory cells in particular, in promoting tumor growth.
引用
收藏
页码:169 / 173
页数:5
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