B regulatory cells in cancer

被引:98
作者
Balkwill, Frances [1 ]
Montfort, Anne [1 ]
Capasso, Melanie [1 ]
机构
[1] Queen Mary Univ London, Barts Canc Inst, Ctr Canc & Inflammat, London EC1M 6BQ, England
关键词
B cells; B regulatory cells; interleukin-10; cancer; anti-CD20; immunosuppression; T-CELLS; CD20; IMMUNOTHERAPY; LYMPHOMA DEPLETION; B10; CELLS; MICE; IL-10; LYMPHOCYTES; SUBSET; TUMORS; AUTOIMMUNITY;
D O I
10.1016/j.it.2012.10.007
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
B regulatory cells are a newly described subpopulation of B cells that appear to play important roles in autoimmunity and more recently, in cancer. In this review we summarize our current knowledge of B regulatory cells, as well as the body of evidence pointing towards a role for B cells in general, and B regulatory cells in particular, in promoting tumor growth.
引用
收藏
页码:169 / 173
页数:5
相关论文
共 50 条
  • [1] Regulatory B cells and T cell Regulation in Cancer
    Horii, Motoki
    Matsushita, Takashi
    JOURNAL OF MOLECULAR BIOLOGY, 2021, 433 (01)
  • [2] The Roles of Regulatory B Cells in Cancer
    He, Yan
    Qian, Hongyan
    Liu, Yuan
    Duan, Lihua
    Li, Yan
    Shi, Guixiu
    JOURNAL OF IMMUNOLOGY RESEARCH, 2014, 2014
  • [3] Distinct cytokines balance the development of regulatory T cells and interleukin-10-producing regulatory B cells
    Holan, Vladimir
    Zajicova, Alena
    Javorkova, Eliska
    Trosan, Peter
    Chudickova, Milada
    Pavlikova, Michaela
    Krulova, Magdalena
    IMMUNOLOGY, 2014, 141 (04) : 577 - 586
  • [4] Regulatory B cells in transplantation: roadmaps to clinic
    Beckett, Joseph
    Hester, Joanna
    Issa, Fadi
    Shankar, Sushma
    TRANSPLANT INTERNATIONAL, 2020, 33 (11) : 1353 - 1368
  • [5] Regulatory B cells in infection, inflammation, and autoimmunity
    Dasgupta, Subhajit
    Dasgupta, Shaoni
    Bandyopadhyay, Mausumi
    CELLULAR IMMUNOLOGY, 2020, 352
  • [6] Perioperative changes in peripheral regulatory B cells of patients with esophageal cancer
    Shi, Jiazhen
    Li, Shibao
    Zhou, Yan
    Wang, Lixin
    Wen, Jiangtao
    Wang, Yonghong
    Kang, Zhihua
    MOLECULAR MEDICINE REPORTS, 2014, 10 (03) : 1525 - 1530
  • [7] Regulatory B cells in infectious disease (Review)
    Dai, You-Chao
    Zhong, Jixin
    Xu, Jun-Fa
    MOLECULAR MEDICINE REPORTS, 2017, 16 (01) : 3 - 10
  • [8] Regulatory B10 Cells Restore Pregnancy Tolerance in a Mouse Model
    Jensen, Federico
    Muzzio, Damian
    Soldati, Rocio
    Fest, Stefan
    Zenclussen, Ana Claudia
    BIOLOGY OF REPRODUCTION, 2013, 89 (04)
  • [9] Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function
    DiLillo, DJ
    Weinberg, J. B.
    Yoshizaki, A.
    Horikawa, M.
    Bryant, J. M.
    Iwata, Y.
    Matsushita, T.
    Matta, K. M.
    Chen, Y.
    Venturi, G. M.
    Russo, G.
    Gockerman, J. P.
    Moore, J. O.
    Diehl, L. F.
    Volkheimer, A. D.
    Friedman, D. R.
    Lanasa, M. C.
    Hall, R. P.
    Tedder, T. F.
    LEUKEMIA, 2013, 27 (01) : 170 - 182
  • [10] The role of regulatory B cells in immune regulation and childhood allergic asthma
    Kliem, Caroline Vanessa
    Schaub, Bianca
    MOLECULAR AND CELLULAR PEDIATRICS, 2024, 11 (01)