The aim of this study was to identify the presence of Helicobacter pylori in nasal polyp specimens of patients with nasal polyposis. A cross-sectional study with control group was performed on fresh tissue samples from 25 patients with nasal polyps, and 25 persons with concha bollusa (control group). Patients with symptoms of gastroesophageal reflux (GERD) were not enrolled. Samples were studied by three methods: polymerase chain reaction (PCR), culture, and urease test. All the diagnostic tests were negative for H. pylori in both the case and control groups. In conclusion, there was no association between H. pylori and nasal polyposis in patients without GERD signs or symptoms in our study, and further studies are needed to assess other potential factors that may influence the development of nasal polyposis.
机构:
Univ Ulsan, Asan Med Ctr, Coll Med, Dept Gastroenterol, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea
Yonsei Univ, Coll Med, Severance Hosp, Dept Gastroenterol,Internal Med, Seoul, South KoreaUniv Ulsan, Asan Med Ctr, Coll Med, Dept Gastroenterol, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea
Pih, Gyu Young
Noh, Jin Hee
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Univ Ulsan, Asan Med Ctr, Coll Med, Dept Gastroenterol, 88 Olymp Ro 43 Gil, Seoul 05505, South KoreaUniv Ulsan, Asan Med Ctr, Coll Med, Dept Gastroenterol, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea
Noh, Jin Hee
Ahn, Ji Yong
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Univ Ulsan, Asan Med Ctr, Coll Med, Dept Gastroenterol, 88 Olymp Ro 43 Gil, Seoul 05505, South KoreaUniv Ulsan, Asan Med Ctr, Coll Med, Dept Gastroenterol, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea
Ahn, Ji Yong
Han, Gill Sang
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Sungkyunkwan Univ, Sch Adv Mat Sci & Engn, 2066 Seobu Ro, Suwon 16419, South KoreaUniv Ulsan, Asan Med Ctr, Coll Med, Dept Gastroenterol, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea