A cross metathesis-based synthesis of analogues of the 2-O-alkyl glycerate part of the moenomycins

被引：10
|
作者：
Eichelberger, U
Mansourova, M
Hennig, L
Findeisen, M
Giesa, S
Müller, D
Welzel, P
机构：
[1] Univ Leipzig, Fak Chem & Mineral, D-04103 Leipzig, Germany
[2] Ruhr Univ Bochum, Inst Analyt Chem, D-44780 Bochum, Germany
来源：
TETRAHEDRON | 2001年 / 57卷 / 48期
关键词：
antibiotics; alkylation; allyl ether; configuration; metathesis;
D O I：
10.1016/S0040-4020(01)00988-7
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Conditions are reported which allow to convert optically active methyl glycerate to the 2-O-allyl derivative without racemization. Cross metathesis reactions then lead to analogues of the 2-O-alkyl glycerate part of the moenomycin antibiotics. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：9737 / 9742
页数：6
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