Cellular and Molecular Bioengineering: A Tipping Point

被引：1

作者：

Brown, Genevieve ^{[1
]}

Butler, Peter J. ^{[2
]}

Chang, David W. ^{[3
]}

Chien, Shu ^{[4
,5
]}

Clegg, Robert M. ^{[6
,7
]}

Dewey, C. Forbes ^{[8
]}

Dong, Cheng ^{[2
]}

Guo, X. Edward ^{[1
]}

Helmke, Brian P. ^{[9
]}

Hess, Henry ^{[1
]}

Jacobs, Christopher R. ^{[1
]}

Kaunas, Roland R. ^{[10
]}

Kumar, Sanjay ^{[11
]}

Lu, Helen H. ^{[1
]}

Mathur, Anshu B. ^{[12
]}

Mow, Van C. ^{[1
]}

Schmid-Schoenbein, Geert W. ^{[13
]}

Skoracki, Roman ^{[3
]}

Wang, Ning ^{[14
]}

Wang, Yingxiao ^{[7
]}

Zhu, Cheng ^{[15
,16
]}

机构：

[1] Columbia Univ, Dept Biomed Engn, New York, NY 10027 USA

[2] Penn State Univ, Dept Bioengn, University Pk, PA 16802 USA

[3] Univ Texas MD Anderson Canc Ctr, Dept Plast Surg, Houston, TX 77030 USA

[4] Univ Calif San Diego, Dept Bioengn, La Jolla, CA 92032 USA

[5] Univ Calif San Diego, Inst Engn Med, La Jolla, CA 92032 USA

[6] Univ Illinois, Dept Phys, Urbana, IL 61801 USA

[7] Univ Illinois, Dept Bioengn, Urbana, IL 61801 USA

[8] MIT, Dept Mech Engn, Cambridge, MA 02139 USA

[9] Univ Virginia, Dept Biomed Engn, Charlottesville, VA 22908 USA

[10] Texas A&M Univ, Dept Biomed Engn, College Stn, TX 77843 USA

[11] Univ Calif Berkeley, Dept Bioengn, Berkeley, CA 94720 USA

[12] Univ Texas MD Anderson Canc Ctr, Dept Plast Surg Res, Houston, TX 77230 USA

[13] Univ Calif San Diego, Dept Bioengn, La Jolla, CA 92093 USA

[14] Univ Illinois, Dept Mech Sci & Engn, Urbana, IL 61801 USA

[15] Georgia Inst Technol, Inst Bioengn & Biosci, Sch Mech Engn, Atlanta, GA 30332 USA

[16] Georgia Inst Technol, Inst Bioengn & Biosci, Sch Biomed Engn, Atlanta, GA 30332 USA

来源：

CELLULAR AND MOLECULAR BIOENGINEERING | 2012年 / 5卷 / 03期

基金：

美国国家科学基金会;

关键词：

Cellular and molecular bioengineering; Mechanobiology; Mechanotransduction; Molecular imaging; Tissue engineering; PROTEIN-KINASE-A; SPATIOTEMPORAL DYNAMICS; FRET; MATRIX; MECHANOBIOLOGY; ACTIVATION; MECHANICS; CELLS; BONE; SRC;

D O I：

10.1007/s12195-012-0246-7

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

In January of 2011, the Biomedical Engineering Society (BMES) and the Society for Physical Regulation in Biology and Medicine (SPRBM) held its inaugural Cellular and Molecular Bioengineering (CMBE) conference. The CMBE conference assembled worldwide leaders in the field of CMBE and held a very successful Round Table discussion among leaders. One of the action items was to collectively construct a white paper regarding the future of CMBE. Thus, the goal of this report is to emphasize the impact of CMBE as an emerging field, identify critical gaps in research that may be answered by the expertise of CMBE, and provide perspectives on enabling CMBE to address challenges in improving human health. Our goal is to provide constructive guidelines in shaping the future of CMBE.

引用

页码：239 / 253

页数：15

共 91 条

[21] Biomechanics: Cell Research and Applications for the Next Decade
Discher, Dennis
Dong, Cheng
Fredberg, Jeffrey J.
Guilak, Farshid
Ingber, Donald
Janmey, Paul
Kamm, Roger D.
Schmid-Schoenbein, Geert W.
Weinbaum, Sheldon
[J]. ANNALS OF BIOMEDICAL ENGINEERING, 2009, 37 (05) : 847 - 859
[22] Dong C, 2011, STUD MECHANOBIOL TIS, V4, P477, DOI 10.1007/8415_2010_21
[23] Nanotechnological strategies for engineering complex tissues
Dvir, Tal
Timko, Brian P.
Kohane, Daniel S.
Langer, Robert
[J]. NATURE NANOTECHNOLOGY, 2011, 6 (01) : 13 - 22
[24] Phase Differential Enhancement of FLIM to Distinguish FRET Components of a Biosensor for Monitoring Molecular Activity of Membrane Type 1 Matrix Metalloproteinase in Live Cells
Eichorst, John Paul
Huang, He
Clegg, Robert M.
Wang, Yingxiao
[J]. JOURNAL OF FLUORESCENCE, 2011, 21 (04) : 1763 - 1777
[25] Probing transcription factor dynamics at the single-molecule level in a living cell
Elf, Johan
Li, Gene-Wei
Xie, X. Sunney
[J]. SCIENCE, 2007, 316 (5828) : 1191 - 1194
[26] Matrix elasticity directs stem cell lineage specification
Engler, Adam J.
Sen, Shamik
Sweeney, H. Lee
Discher, Dennis E.
[J]. CELL, 2006, 126 (04) : 677 - 689
[27] A Hitchhiker's Guide to Mechanobiology
Eyckmans, Jeroen
Boudou, Thomas
Yu, Xiang
Chen, Christopher S.
[J]. DEVELOPMENTAL CELL, 2011, 21 (01) : 35 - 47
[28] Inflammatory markers and coronary artery disease
Fichtlscherer, S
Heeschen, C
Zeiher, AM
[J]. CURRENT OPINION IN PHARMACOLOGY, 2004, 4 (02) : 124 - 131
[29] Cell mechanics and the cytoskeleton
Fletcher, Daniel A.
Mullins, Dyche
[J]. NATURE, 2010, 463 (7280) : 485 - 492
[30] Franks AL, 2012, ANTICANCER RES, V32, P1119

← 1 2 3 4 5 6 7 8 9 10 →