Application of Laser-Backscattering Instruments for In Situ Monitoring of Crystallization Processes - A Review

被引：49

作者：

Heinrich, Joerg ^{[1
]}

Ulrich, Joachim ^{[1
]}

机构：

[1] Univ Halle Wittenberg, Ctr Engn Thermal Proc Technol, D-06120 Halle, Saale, Germany

来源：

CHEMICAL ENGINEERING & TECHNOLOGY | 2012年 / 35卷 / 06期

关键词：

Chord length distribution; Crystallization; Focused beam reflectance measurement; Particle size analysis; Threefold dynamical optical reflectance measurement; BEAM REFLECTANCE MEASUREMENT; PARTICLE-SIZE DISTRIBUTION; BATCH-COOLING CRYSTALLIZATION; CHORD-LENGTH DISTRIBUTIONS; L-GLUTAMIC ACID; ANTISOLVENT CRYSTALLIZATION; ANTI-SOLVENT; PREFERENTIAL CRYSTALLIZATION; INDUSTRIAL CRYSTALLIZATION; POLYMORPHIC TRANSFORMATION;

D O I：

10.1002/ceat.201100344

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Laser-backscattering instruments, such as the focused beam reflectance measurement or threefold dynamical optical reflectance measurement, are promising tools to aid crystallization process development, allowing an in situ, real-time, and nondestructive measurement of particle size distributions. Besides the instrument principles, in detail geometrical and optical models are discussed which deconvolute the recorded chord length distribution. Emphasis is thereby laid on the influence of the suspension density on instrument recordings. The application of laser-backscattering devices for determination of kinetic constants is discussed and future directions and perspectives are given.

引用

页码：967 / 979

页数：13

共 119 条

[11]

BRAATZ RD, 2002, AICHE S SERIES, V326, P307

[12] Comparison between open-loop temperature control and closed-loop supersaturation control for cooling crystallization of glycine [J].

Chew, Jia Wei ;

Black, Simon N. ;

Chow, Pui Shan ;

Tan, Reginald B. H. .

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2007, 46 (03) :830-838

[13] Application of a recent FBRM-probe model to quantify preferential crystallization of DL-threonine [J].

Czapla, F. ;

Kail, N. ;

Oencuel, A. ;

Lorenz, H. ;

Briesen, H. ;

Seidel-Morgenstern, A. .

CHEMICAL ENGINEERING RESEARCH & DESIGN, 2010, 88 (11A) :1494-1504

[14] Parameterization of population balance models for polythermal auto seeded preferential crystallization of enantiomers [J].

Czapla, F. ;

Haida, H. ;

Elsner, M. P. ;

Lorenz, H. ;

Seidel-Morgenstern, A. .

CHEMICAL ENGINEERING SCIENCE, 2009, 64 (04) :753-763

[15] The influence of impurities on phosphoric acid hemihydrate crystallization [J].

Dang, Leping ;

Wei, Hongyuan ;

Zhu, Zheng ;

Wang, Jingkang .

JOURNAL OF CRYSTAL GROWTH, 2007, 307 (01) :104-111

[16]

Daniels R., 2004, SKIN CARE FORUM ONLI, V36

[17]

Daymo E. A., 1998, P INT SOC OPT ENG NU, V3539

[18] Process control of seeded batch cooling crystallization of the metastable α-form glycine using an in-situ ATR-FTIR spectrometer and an in-situ FBRM particle counter [J].

Doki, N ;

Seki, H ;

Takano, K ;

Asatani, H ;

Yokota, M ;

Kubota, N .

CRYSTAL GROWTH & DESIGN, 2004, 4 (05) :949-953

[19] Factors governing emulsion droplet and solid particle size measurements performed using the focused beam reflectance technique [J].

Dowding, PJ ;

Goodwin, JW ;

Vincent, B .

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2001, 192 (1-3) :5-13

[20]

Duennebier G, 2007, CHEM-ING-TECH, V79, P2019, DOI 10.1002/cite.200700156

← 1 2 3 4 5 6 7 8 9 10 →