Anticomplement activity of various solvent extracts from Korea local Artemisia spp.

被引：4

作者：

Moon, Hyung-In ^{[1
]}

Jung, Seil ^{[2
,3
]}

Lee, Young-Choon ^{[4
]}

Lee, Jai-Heon ^{[1
]}

机构：

[1] Dong A Univ, Coll Nat Resources & Life Sci, Dept Med Biotechnol, Pusan 604714, South Korea

[2] Dong A Univ, Coll Med, Dept Urol, Pusan 604714, South Korea

[3] Dong A Univ, Dong A Antiaging Res Inst, Pusan 604714, South Korea

[4] Dong A Univ, Coll Nat Resources & Life Sci, Dept Biotechnol, Pusan 604714, South Korea

来源：

IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY | 2012年 / 34卷 / 01期

关键词：

Artemisia; Artemisia rubripes Nakai; Artemisia montana (Nakai) Pamp; anticomplement activity; classical pathway; ANTI-COMPLEMENT ACTIVITY; CONSTITUENTS;

D O I：

10.3109/08923973.2011.581286

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The study evaluated the anticomplement activity from various solvent extracts of eight Artemisia plants (Artemisia capillaris Thunb., Artemisia fukudo Makino., Artemisia japonica Thunb., Artemisia montana (Nakai) Pamp., Artemisia keiskeana Miq., Artemisia rubripes Nakai., Artemisia stolonifera (Maxim.) Kom., and Artemisia sylvatica Max.) from South Korea on the classical pathway (CP). We have evaluated various organic solvent extract from eight Artemisia plants with regard to its anticomplement activity on the CP. A. rubripes and A. montana chloroform extracts showed inhibitory activity against complement system with 50% inhibitory concentrations (IC50) values of 54.3 and 64.2 mu g/mL. This is the first report of anticomplement activity from Artemisia plants.

引用

页码：95 / 97

页数：3

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