Reaction of a Copper(II)-Nitrosyl Complex with Hydrogen Peroxide: Phenol Ring Nitration through a Putative Peroxynitrite Intermediate

被引:18
作者
Kalita, Apurba [1 ]
Deka, Ramesh C. [2 ]
Mondal, Biplab [1 ]
机构
[1] Indian Inst Technol, Dept Chem, Gauhati 781039, Assam, India
[2] Tezpur Univ, Dept Chem Sci, Tezpur 784028, Assam, India
关键词
NITRIC-OXIDE REDUCTION; ALKOXO-OXYGEN ATOM; MAGNETIC-PROPERTIES; CRYSTAL-STRUCTURE; TYROSINE NITRATION; AQUEOUS-SOLUTION; CHEMISTRY; MECHANISM; SUPEROXIDE; OXIDATION;
D O I
10.1021/ic400890f
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Copper(II) complex, 1, with the histidine-derived ligand L (L = methyl 2-(2-hydroxybenzylamino)-3-(1H-imidazol-5-yl)propanoate) has been synthesized and characterized. Single-crystal structure determination reveals a diphenolato-bridged dicopper(II) core in 1. Addition of (NO)-N-center dot to an acetonitrile solution of 1 affords the corresponding mononuclear copper(II)-nitrosyl complex, 2. In the presence of H2O2, 2 results in formation of the corresponding copper(I)-peroxynitrite. Formation of peroxynitrite (-OONO) intermediate is evident from its characteristic phenol ring nitration reaction which resembles the tyrosine nitration in biological systems. Further, isolation. of nitrate (NO3-) as the decomposition product from 2 at room temperature also supports the involvement of -OONO intermediate.
引用
收藏
页码:10897 / 10903
页数:7
相关论文
empty
未找到相关数据