OPTN/SRTR 2012 Annual Data Report: lung

被引:71
作者
Valapour, M. [1 ,2 ]
Skeans, M. A. [1 ]
Heubner, B. M. [1 ]
Smith, J. M. [1 ,3 ]
Schnitzler, M. A. [1 ,4 ]
Hertz, M. I. [1 ,2 ]
Edwards, L. B.
Snyder, J. J.
Israni, A. K.
Kasiske, B. L.
机构
[1] Minneapolis Med Res Fdn Inc, Sci Registry Transplant Recipients, Minneapolis, MN USA
[2] Univ Minnesota, Dept Med, Div Pulm Allergy Crit Care & Sleep Med, Minneapolis, MN 55455 USA
[3] Univ Washington, Dept Pediat, Seattle, WA 98195 USA
[4] St Louis Univ, Sch Med, Ctr Outcomes Res, St Louis, MO USA
关键词
End-stage lung diseases; Lung Allocation Score; lung transplant; organ allocation; transplant outcomes;
D O I
10.1111/ajt.12584
中图分类号
R61 [外科手术学];
学科分类号
摘要
Lung transplants are increasingly used as treatment for end-stage lung diseases not amenable to other medical and surgical therapies. Lungs are allocated to adult and adolescent transplant candidates on the basis of age, geography, blood type compatibility, and the Lung Allocation Score, which reflects risk of wait-list mortality and probability of posttransplant survival. The overall median waiting time in 2012 was 4 months, and 65.3% of candidates underwent transplant within 1 year of listing; however, this proportion varied greatly by donation service area. Unadjusted median survival of lung transplant recipients was 5.3 years in 2012, and median survival conditional on living for 1 year posttransplant was 6.7 years. Among pediatric lung candidates in 2012, 32.1% were wait-listed for less than 1 year, 17.9% for 1 to less than 2 years, 16.7% for 2 to less than 4 years, and 33.3% for 4 or more years. Both graft and patient survival have continued to improve; survival rates for recipients aged 6-11 years are better than for younger recipients. Compared with recipients of other solid organ transplants, lung transplant recipients experienced the highest rates of rehospitalization for transplant complications: 43.7 per 100 patients in year 1 and 36.0 in year 2.
引用
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页码:139 / 165
页数:27
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