Proteolysis and cell migration: creating a path?

被引：336
作者：
Murphy, G [1 ]
Gavrilovic, J [1 ]
机构：
[1] Univ E Anglia, Sch Biol Sci, Norwich NR4 7TJ, Norfolk, England
来源：
CURRENT OPINION IN CELL BIOLOGY | 1999年 / 11卷 / 05期
基金：
英国惠康基金;
关键词：
D O I：
10.1016/S0955-0674(99)00022-8
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Both serine and metalloproteinases have been implicated in the complex integrated events underlying cell migration but no definitive single mechanism has emerged. Work over the past two years linking both membrane and soluble proteinases with integrins and other adhesion proteins and with intracellular signalling systems could herald the beginnings of a potential expansion of our understanding of the role and regulation of proteolysis in cell migration.
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收藏
页码：614 / 621
页数：8
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