Mass-forming intrahepatic cholangiocarcinoma: Enhancement patterns in the arterial phase of dynamic hepatic CT - Correlation with clinicopathological findings

被引：88

作者：

Fujita, Nobuhiro ^{[1
]}

Asayama, Yoshiki ^{[1
]}

Nishie, Akihiro ^{[1
]}

Ishigami, Kousei ^{[1
]}

Ushijima, Yasuhiro ^{[1
]}

Takayama, Yukihisa ^{[2
]}

Okamoto, Daisuke ^{[1
]}

Moirta, Koichiro ^{[1
]}

Shirabe, Ken ^{[3
]}

Aishima, Shinichi ^{[4
]}

Wang, Huanlin ^{[5
]}

Oda, Yoshinao ^{[5
]}

Honda, Hiroshi ^{[1
]}

机构：

[1] Kyushu Univ, Grad Sch Med Sci, Dept Clin Radiol, Higashi Ku, 3-1-1 Maidashi, Fukuoka 8128582, Japan

[2] Kyushu Univ, Grad Sch Med Sci, Dept Radiol Informat & Network, Higashi Ku, 3-1-1 Maidashi, Fukuoka 8128582, Japan

[3] Kyushu Univ, Grad Sch Med Sci, Dept Surg & Sci, Higashi Ku, 3-1-1 Maidashi, Fukuoka 8128582, Japan

[4] Saga Univ Hosp, Dept Pathol & Microbiol, Fac Med, Nabesima 5-1-1, Saga, Saga 8498501, Japan

[5] Kyushu Univ, Grad Sch Med Sci, Dept Anat Pathol, Higashi Ku, 3-1-1 Maidashi, Fukuoka 8128582, Japan

来源：

EUROPEAN RADIOLOGY | 2017年 / 27卷 / 02期

关键词：

Intrahepatic cholangiocarcinoma; Perihilar cholangiocarcinoma; Peripheral cholangiocarcinoma; Computed tomography; Arterial enhancement pattern; PERIPHERAL-TYPE; PROPOSAL; TRACT;

D O I：

10.1007/s00330-016-4386-3

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

To evaluate the relationship between the enhancement pattern of intrahepatic cholangiocarcinomas (ICCs) in the hepatic arterial phase (HAP) of dynamic hepatic CT and the clinicopathological findings with special reference to the perihilar type and the peripheral type. Forty-seven patients with pathologically proven ICCs were enrolled. Based on the enhancement pattern in the HAP, the lesions were classified into three groups: a hypovascular group (n=13), rim-enhancement group (n=18), and hypervascular group (n=16). The clinicopathological findings were compared among the three groups. Perihilar-type ICCs were significantly more frequently observed in the hypovascular group than in the rim-enhancement and hypervascular groups (p=0.006 and p < 0.001, respectively). Lymphatic invasion, perineural invasion, and biliary invasion were significantly more frequent in the hypovascular group than the rim- enhancement group (p=0.001, p=0.025 and p=0.029, respectively) or hypervascular group (p < 0.001, p < 0.001 and p=0.025, respectively). Patients with hypovascular lesions showed significantly poorer disease-free survival than patients with rim-enhancing or hypervascular lesions (p=0.001 and p=0.001, respectively). Hypovascularity was an independent preoperative prognostic factor for disease-free survival (p < 0.001). Hypovascular ICCs in the HAP tend to be of perihilar type and to have more malignant potential than other ICCs. aEuro cent Hypovascular ICCs have greater malignant potential than rim-enhancing and hypervascular ICCs. aEuro cent Hypovascular ICCs show a higher frequency of perihilar-type ICCs. aEuro cent Perihilar-type ICCs do not always display distal ductal wall thickening.

引用

页码：498 / 506

页数：9

共 24 条

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