Proposal for the use in emergency departments of cardiac troponins measured with the latest generation methods in patients with suspected acute coronary syndrome without persistent ST-segment elevation

被引:52
作者
Casagranda, Ivo [1 ]
Cavazza, Mario [2 ]
Clerico, Aldo [3 ,4 ]
Galvani, Marcello [5 ]
Ottani, Filippo [5 ]
Zaninotto, Martina [6 ]
Biasucci, Luigi Maria [7 ]
Cervellin, Gianfranco [8 ]
Lenzi, Tiziano [9 ]
Lippi, Giuseppe [10 ]
Plebani, Mario [6 ]
Tubaro, Marco [11 ]
机构
[1] St Antonio & Biagio & Cesare Arrigo Hosp, Emergency Dept, Alessandria, Italy
[2] St Orsola Malpighi Hosp, Emergency Dept, Bologna, Italy
[3] Fdn G Monasterio CNR Reg Toscana, Pisa, Italy
[4] Scuola Super Sant Anna, Pisa, Italy
[5] Morgagni Pierantoni Hosp, Div Cardiol, Forli, Italy
[6] Univ Hosp, Dept Lab Med, Padua, Italy
[7] Univ Cattolica Sacro Cuore, Dept Cardiovasc Med, I-00168 Rome, Italy
[8] Acad Hosp Parma, Emergency Dept, Parma, Italy
[9] Osped Civile Santa Maria della Scaletta, Emergency Dept, Imola, Italy
[10] Acad Hosp Parma, Lab Clin Chem & Hematol, Parma, Italy
[11] San Filippo Neri Hosp, Cardiovasc Dept, Rome, Italy
关键词
acute coronary syndrome; cardiac troponin; emergency departments; high-sensitivity assays; non-ST-segment elevation; 99th percentile; MYOCARDIAL-INFARCTION;
D O I
10.1515/cclm-2013-0423
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
The purpose of this document is to develop recommendations on the use of the latest generation of cardiac troponins in emergency room settings for the diagnosis of myocardial infarction in patients with suspected acute coronary syndrome (ACS) without persistent ST-segment elevation (NSTE-ACS). The main points which have been addressed reaching a consensus are represented by: 1. Suitability and appropriateness of the terminology. 2. Appropriateness of the request. 3. Confirmation of the diagnosis of myocardial infarction (rule-in). 4. Exclusion of the diagnosis of myocardial infarction (rule-out). Work method: Each point has been analyzed by taking into account the evidence presented in medical publications. Recommendations were developed using the criteria adopted by the European Society of Cardiology and the American Heart Association/American College of Cardiology (www.escardio.org/guidelines). Each point of the recommendation was submitted for validation to an external audit by a Group of Experts (named above).
引用
收藏
页码:1727 / 1737
页数:11
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