Human ESC-Derived Interneurons Improve Major Consequences of Spinal Cord Injury

被引：9

作者：

Blesch, Armin ^{[1
,2
]}

机构：

[1] Stark Neurosci Res Inst, Dept Neurol Surg, Indianapolis, IN 46202 USA

[2] Stark Neurosci Res Inst, Spinal Cord & Brain Injury Res Grp, Goodman Campbell Brain & Spine, Indianapolis, IN 46202 USA

来源：

Cell Stem Cell | 2016年 / 19卷 / 04期

关键词：

D O I：

10.1016/j.stem.2016.09.008

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Beyond impaired motor and sensory function, neuropathic pain and loss of bladder control caused by spinal cord injuries (SCIs) can severely affect quality of life. In this issue of Cell Stem Cell, Fandel et al. (2016) show that transplanted human ESC-derived cells biased to produce inhibitory interneurons significantly improve pain and bladder function in rodent SCI models.

引用

页码：423 / 424

页数：2

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