Caryophyllene sesquiterpenoids from a fungicolous isolate of Pestalotiopsis disseminata

被引：72
作者：
Deyrup, ST
Swenson, DC
Gloer, JB [1 ]
Donald, TW
机构：
[1] Univ Iowa, Dept Chem, Iowa City, IA 52242 USA
[2] ARS, Mycotoxin Res Unit, Natl Ctr Agr Utilizat Res, USDA, Peoria, IL 61604 USA
来源：
JOURNAL OF NATURAL PRODUCTS | 2006年 / 69卷 / 04期
关键词：
D O I：
10.1021/np050460b
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Three new caryophyllene-type sesquiterpene alcohols, 6-hydroxypunctaporonin E (1), 6-hydroxypunctaporonin B (2), and 6-hydroxypunctaporonin A (3), have been isolated from cultures of the fungicolous fungus Pestalotiopsis disseminata. The structures of 1-3 were determined mainly by analysis of 1D and 2D NMR data. The structure and absolute configuration of 6-hydroxypunctaporonin E (1) was confirmed through X-ray crystallographic analysis of its mono-bromobenzoate derivative. Compounds 1 and 2 showed activity against Gram-positive bacteria.
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页码：608 / 611
页数：4
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