Management of Spastic Disorders of the Esophagus

被引:78
作者
Roman, Sabine [1 ]
Kahrilas, Peter J. [2 ]
机构
[1] Univ Lyon 1, Hosp Civils Lyon, Hop Edouard Herriot, F-69437 Lyon 03, France
[2] Northwestern Univ, Feinberg Sch Med, Dept Med, Chicago, IL 60611 USA
基金
美国国家卫生研究院;
关键词
Distal esophageal spasm; Achalasia; Jackhammer esophagus; High-resolution manometry; Esophageal motility; HIGH-RESOLUTION MANOMETRY; NONCARDIAC CHEST-PAIN; LONGITUDINAL MUSCLE-CONTRACTION; NUTCRACKER ESOPHAGUS; PRESSURE TOPOGRAPHY; MOTILITY DISORDERS; HIGH-AMPLITUDE; BOTULINUM TOXIN; MOTOR FUNCTION; NITRIC-OXIDE;
D O I
10.1016/j.gtc.2012.11.002
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The concept of esophageal spastic disorders encompasses spastic achelasia, distal esophageal spasm, and jackhammer esophagus. These are conceptually distinct in that spastic achalasia and distal esophageal spasm are characterized by a loss of neural inhibition, whereas jackhammer esophagus is associated with hypercontractility. Hypercontractility may also occur as a result of esophagogastric junction outflow obstruction or inflammation. The diagnosis of jackhammer esophagus as a primary motility disorder is based on the characteristic manometric findings after ruling out mechanical obstruction and eosinophilic. esophagitis. Despite the differences in pathophysiology among the esophageal spastic disorders, their management is similar.
引用
收藏
页码:27 / +
页数:18
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