Targeting the β-Adrenergic Receptor System Through G-Protein-Coupled Receptor Kinase 2: A New Paradigm for Therapy and Prognostic Evaluation in Heart Failure From Bench to Bedside

被引：65

作者：

Rengo, Giuseppe ^{[1
,2
]}

Perrone-Filardi, Pasquale ^{[2
]}

Femminella, Grazia D. ^{[2
]}

Liccardo, Daniela ^{[2
]}

Zincarelli, Carmela ^{[1
,2
]}

de Lucia, Claudio ^{[2
]}

Pagano, Gennaro ^{[2
]}

Marsico, Fabio ^{[2
]}

Lymperopoulos, Anastasios ^{[3
]}

Leosco, Dario ^{[2
]}

机构：

[1] IRCCS, Salvatore Maugeri Fdn, Telese Terme, BN, Italy

[2] Univ Naples Federico II, Dept Internal Med Cardiovasc & Immunol Sci, I-80131 Naples, Italy

[3] Nova SE Univ, Dept Pharmaceut Sci, Coll Pharm, Ft Lauderdale, FL 33314 USA

来源：

CIRCULATION-HEART FAILURE | 2012年 / 5卷 / 03期

关键词：

heart failure; G-protein-coupled receptor kinase 2; beta-adrenergic receptor; prognosis; GENE-TRANSFER; BETA-ARK1; INHIBITION; CARDIAC-FUNCTION; GRK2; EXPRESSION; ADRENOCEPTORS; MANIPULATION; MECHANISM; SURVIVAL; MYOCYTES;

D O I：

10.1161/CIRCHEARTFAILURE.112.966895

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：385 / 391

页数：7

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