Recent Advances in the Synthesis of New Antimycobacterial Agents Based on the 1H-1,2,3-Triazoles

被引：42

作者：

Gonzaga, Daniel Tadeu G. ^{[1
]}

da Rocha, David R. ^{[1
]}

da Silva, Fernando de C. ^{[1
]}

Ferreira, Vitor F. ^{[1
]}

机构：

[1] Univ Fed Fluminense, Inst Quim, Dept Quim Organ, BR-24020150 Niteroi, RJ, Brazil

来源：

CURRENT TOPICS IN MEDICINAL CHEMISTRY | 2013年 / 13卷 / 22期

关键词：

Antimycobacterial agents; inhibitors of glycosidases; 1H-1,2,3-triazoles; 1,4-1H-1,2,3-triazoles; 1,4,5-1H-1,2,3-triazoles; tuberculosis; INOSINE MONOPHOSPHATE DEHYDROGENASE; HUISGEN 3+2 CYCLOADDITION; CLICK CHEMISTRY; 1,2,3-TRIAZOLE DERIVATIVES; ANTITUBERCULAR ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; BIOLOGICAL EVALUATION; TRIAZOLE DERIVATIVES; ADENINE-DINUCLEOTIDE; INHIBITORY-ACTIVITY;

D O I：

10.2174/15680266113136660202

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The 1H-1,2,3-triazoles have been studied for many years as an important class of heterocyclic compounds and still attracting considerable attention due to their several application such as, organocatalyst, ionic liquid and broad range of biological activities, including several neglected diseases as tuberculosis. This review emphasizes the recent advances of these triazoles and their perspective in the development of new bioactive chemical entities against tuberculosis.

引用

页码：2850 / 2865

页数：16

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