Facile Synthesis of New [1,2,4]Triazolo[4,3-b]pyridazine

被引：6

作者：

Arghiani, Z. ^{[1
]}

Seyedi, S. M. ^{[1
]}

Bakavoli, M. ^{[1
]}

Eshghi, H. ^{[1
]}

机构：

[1] Ferdowsi Univ Mashhad, Sch Sci, Dept Chem, Mashhad 917751436, Iran

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2015年 / 52卷 / 04期

关键词：

15-LIPOXYGENASE INHIBITORS; ANXIOLYTIC ACTIVITY; DERIVATIVES; AGONIST; POTENT; TRIAZOLOPYRIDAZINE; PYRIDAZINE;

D O I：

10.1002/jhet.2207

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A number of new [1,2,4]triazolo[4,3-b]pyridazines were prepared by either cyclocondesation of substituted hydrazinopyridazines with orthoesters or oxidative cyclization of their hydrazone analogs in nitrobenzene as an oxidizing agent. A host of other new [1,2,4]triazolo[4,3-b]pyridazine derivatives were synthesized by sequential treatment of the latter compounds with carbon disulfide and alkyl halides.

引用

页码：1099 / 1107

页数：9

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