Single Walled Carbon Nanotubes/polypyrrole-GOx composite films to modify gold microelectrodes for glucose biosensors: Study of the extended linearity

被引：43

作者：

Valentini, F. ^{[1
]}

Galache Fernandez, L. ^{[2
]}

Tamburri, E. ^{[1
]}

Palleschi, G. ^{[1
]}

机构：

[1] Univ Roma Tor Vergata, Dipartimento Chim, I-00133 Rome, Italy

[2] Univ A Coruna, La Coruna, Spain

来源：

BIOSENSORS & BIOELECTRONICS | 2013年 / 43卷

关键词：

EPD deposition; Single-Wall Carbon Nanotubes; SWCNT/PPy nanocomposites; Permeability; Perm-selectivity; Microelectrodes; POLYPYRROLE; OXIDASE;

D O I：

10.1016/j.bios.2012.11.019

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A glucose biosensor was assembled using gold microelectrodes (diameter of 250 mu m) coated by Single-Walled Carbon Nanotubes (SWCNTs), via the Electrophoresis Deposition Process (EPD). This nanostructured platform was successfully used to deposit the poly(pyrrole)/glucose oxidase film (PPy/GOx). The most important result of this biosensors was the wide linear range of concentration, ranging from 4 to 100 mM (covering the hypo- and hyper-glycemia range, useful in diabetes). This extended linearity offered the possibility to measure glucose from 0.560 to 12.0 mM, with a detection limit of 50 mu M (useful for hypo-glycemia disease). (c) 2012 Elsevier B.V. All rights reserved.

引用

页码：75 / 78

页数：4

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