Guidelines for the management of hemophilia

被引:1421
作者
Srivastava, A. [1 ]
Brewer, A. K. [2 ]
Mauser-Bunschoten, E. P. [3 ,4 ]
Key, N. S. [5 ]
Kitchen, S. [6 ]
Llinas, A. [7 ,8 ,9 ]
Ludlam, C. A. [10 ]
Mahlangu, J. N. [11 ,12 ,13 ]
Mulder, K. [14 ]
Poon, M. C. [15 ,16 ,17 ,18 ,19 ]
Street, A. [20 ]
机构
[1] Christian Med Coll & Hosp, Dept Hematol, Vellore 632004, Tamil Nadu, India
[2] Royal Infirm, Dept Oral Surg, Glasgow G31 2ER, Lanark, Scotland
[3] Univ Med Ctr Utrecht, Van Creveldklin, Utrecht, Netherlands
[4] Univ Med Ctr Utrecht, Dept Hematol, Utrecht, Netherlands
[5] Univ N Carolina, Dept Med, Chapel Hill, NC USA
[6] Royal Hallamshire Hosp, Sheffield Haemophilia & Thrombosis Ctr, Sheffield S10 2JF, S Yorkshire, England
[7] Fdn Santa Fe Univ Hosp Fdn Cosme & Damian, Dept Orthopaed & Traumatol, Bogota, Colombia
[8] Univ Los Andes, Bogota, Colombia
[9] Univ Rosario, Bogota, Colombia
[10] Royal Infirm, Comprehens Care Haemophilia & Thrombosis Ctr, Edinburgh, Midlothian, Scotland
[11] Johannesburg Hosp, Haemophilia Comprehens Care Ctr, Johannesburg, South Africa
[12] Natl Hlth Lab Serv, Fac Hlth Sci, Dept Mol Med & Haematol, Johannesburg, South Africa
[13] Univ Witwatersrand, Johannesburg, South Africa
[14] Hlth Sci Ctr, Bleeding Disorders Clin, Winnipeg, MB, Canada
[15] Univ Calgary, Dept Med, Foothills Hosp, Calgary, AB, Canada
[16] Univ Calgary, Dept Pediat, Foothills Hosp, Calgary, AB T2N 1N4, Canada
[17] Univ Calgary, Dept Oncol, Foothills Hosp, Calgary, AB, Canada
[18] Univ Calgary, Foothills Hosp, So Alberta Rare Blood & Bleeding Disorders Compre, Calgary, AB, Canada
[19] Calgary Hlth Reg, Calgary, AB, Canada
[20] Alfred Hosp, Melbourne, Vic, Australia
关键词
bleeding disorders; guidelines; hemophilia; management; treatment; IMMUNE TOLERANCE INDUCTION; TOTAL KNEE ARTHROPLASTY; HEPATITIS-B-VACCINE; QUALITY-OF-LIFE; FACTOR-VIII CONCENTRATE; ISCHEMIC-HEART-DISEASE; VON-WILLEBRAND-DISEASE; FRESH-FROZEN PLASMA; TERM-FOLLOW-UP; BLEEDING DISORDERS;
D O I
10.1111/j.1365-2516.2012.02909.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hemophilia is a rare disorder that is complex to diagnose and to manage. These evidence-based guidelines offer practical recommendations on the diagnosis and general management of hemophilia, as well as the management of complications including musculoskeletal issues, inhibitors, and transfusion-transmitted infections. By compiling these guidelines, the World Federation of Hemophilia aims to assist healthcare providers seeking to initiate and/or maintain hemophilia care programs, encourage practice harmonization around the world and, where recommendations lack adequate evidence, stimulate appropriate studies.
引用
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页码:E1 / E47
页数:47
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