Liver transplantation: Yesterday, today and tomorrow

被引：32
作者：
Abbasoglu, Osman [1 ]
机构：
[1] Hacettepe Univ, Sch Med, Dept Surg, TR-06100 Ankara, Turkey
来源：
WORLD JOURNAL OF GASTROENTEROLOGY | 2008年 / 14卷 / 20期
关键词：
liver transplantation; hepatitis C virus; hepatitis B virus; hepatocellular carcinoma; ABO incompatibility; living donor;
D O I：
10.3748/wjg.14.3117
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
With the advances in technical skills, management of postoperative complications and improvements in immunosuppressive drugs, liver transplantation is the standard treatment for many patients with chronic liver disease. Today, shortage of donor organs seems to be the major limiting factor for the application of liver transplantation. This review focuses on five issues that are challenging to clinical practice of liver transplantation and relevant to gastroenterologists. These include living donor liver transplantation, recurrent viral hepatitis, non-heart-beating donors, hepatocellular carcinoma, and ABO incompatible liver transplantation. Living donor and non-heart beating donor transplantations were initiated as a solution to increase the donor organ pool and it is expected that there will be an increase in the number of these donors. Recurrent hepatitis C and hepatocellular carcinoma following liver transplantation are among major problems and ongoing research in these diseases may lead to better outcomes in these recipients. (C) 2008 The WJG Press. All rights reserved.
引用
收藏
页码：3117 / 3122
页数：6
相关论文
共 50 条
[1]   Ten years of liver transplantation - An evolving understanding of late graft loss [J].
Abbasoglu, O ;
Levy, MF ;
Brkic, BB ;
Testa, G ;
Jeyarajah, DR ;
Goldstein, RM ;
Husberg, BS ;
Gonwa, TA ;
Klintmalm, GB .
TRANSPLANTATION, 1997, 64 (12) :1801-1807
[2]   Liver transplantation from controlled non-heartbeating donors: An increased incidence of biliary complications [J].
Abt, P ;
Crawford, M ;
Desai, N ;
Markmann, J ;
Olthoff, K ;
Shaked, A .
TRANSPLANTATION, 2003, 75 (10) :1659-1663
[3]   Survival following liver transplantation from non-heart-beating donors [J].
Abt, PL ;
Desai, NM ;
Crawford, MD ;
Forman, LM ;
Markmann, JW ;
Olthoff, KM ;
Markmann, JF .
ANNALS OF SURGERY, 2004, 239 (01) :87-92
[4]   Critical graft size in adult-to-adult living donor liver transplantation: Impact of the recipient's disease [J].
Ben-Haim, M ;
Emre, S ;
Fishbein, TM ;
Sheiner, PA ;
Bodian, CA ;
Kim-Schluger, L ;
Schwartz, ME ;
Miller, CM .
LIVER TRANSPLANTATION, 2001, 7 (11) :948-953
[5]   Small hepatocellular carcinoma in child a cirrhotic patients:: Hepatic resection versus transplantation [J].
Bigourdan, JM ;
Jaeck, D ;
Meyer, N ;
Meyer, C ;
Oussoultzoglou, E ;
Bachellier, P ;
Weber, JC ;
Audet, M ;
Doffoël, M ;
Wolf, P .
LIVER TRANSPLANTATION, 2003, 9 (05) :513-520
[6]   Prognostic prediction and treatment strategy in hepatocellular carcinoma [J].
Bruix, J ;
Llovet, JM .
HEPATOLOGY, 2002, 35 (03) :519-524
[7]  
Cheng SJ, 2001, TRANSPLANTATION, V72, P861
[8]   Prevention of hepatitis B virus recurrence after liver transplantation [J].
Eisenbach, Christoph ;
Sauer, Peter ;
Mehrabi, Arianeb ;
Stremmel, Wolfgang ;
Encke, Jens .
CLINICAL TRANSPLANTATION, 2006, 20 :111-116
[9]   Surgical treatment of hepatocellular carcinoma beyond milan criteria. Results of liver resection, salvage transplantation, and primary liver transplantation [J].
Facciuto, Marcelo E. ;
Koneru, Baburao ;
Rocca, Juan P. ;
Wolf, David C. ;
Kim-Schluger, Leona ;
Visintainer, Paul ;
Klein, Kenneth M. ;
Chun, Hoo ;
Marvin, Michael ;
Rozenblit, Grigory ;
Rodriguez-Davalos, Manuel ;
Sheiner, Patricia A. .
ANNALS OF SURGICAL ONCOLOGY, 2008, 15 (05) :1383-1391
[10]   Living-donor liver transplantation for hepatocellular carcinoma [J].
Furukawa, Hiroyuki ;
Shimamura, Tsuyoshi ;
Suzuki, Tomomi ;
Taniguchi, Masahiko ;
Yamashita, Kenichiro ;
Kamiyama, Toshiya ;
Matsushita, Michiaki ;
Todo, Satoru .
JOURNAL OF HEPATO-BILIARY-PANCREATIC SURGERY, 2006, 13 (05) :393-397
12345