Drug-loaded superparamagnetic iron oxide nanoparticles for combined cancer imaging and therapy in vivo

被引：483

作者：

Yu, Mi Kyung ^{[1
]}

Jeong, Yong Yeon ^{[2
]}

Park, Jinho ^{[1
]}

Park, Sangjin ^{[1
]}

Kim, Jin Woong ^{[2
]}

Min, Jung Jun ^{[2
]}

Kim, Kyuwon ^{[3
]}

Jon, Sangyong ^{[1
]}

机构：

[1] GIST, Dept Life Sci, Res Ctr Biomol Nanotechnol, Kwangju 500712, South Korea

[2] Chonnam Natl Univ, Sch Med, Dept Radiol, Kwangju 501746, South Korea

[3] Univ Incheon, Dept Chem, Inchon, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 29期

关键词：

antitumor agents; drug delivery; imaging agents; nanotechnology;

D O I：

10.1002/anie.200800857

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Multitasking rust ball: The questions of where a tumor is located, whether drugs are properly delivered to the tumor, and what the therapeutic response of the tumor is, could be answered by using simple but smart, drug-loaded superparamagnetic iron oxide nanoparticles that can accumulate in tumor with high efficiency thanks to the presence of rationally engineered polymer coating layers.

引用

页码：5362 / 5365

页数：4

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