Metabolic complications of antiretroviral therapy in children

被引：63
作者：
Leonard, EG
McComsey, GA
机构：
[1] Rainbow Babies & Childrens Hosp, Div Pediat Infect Dis, Cleveland, OH 44106 USA
[2] Case Western Reserve Univ, Ctr AIDS Res, Cleveland, OH 44106 USA
来源：
PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2003年 / 22卷 / 01期
关键词：
D O I：
10.1097/00006454-200301000-00018
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Survival in HIV-infected children has greatly improved with the introduction of highly active antiretroviral therapy. Children are more vulnerable than adults to metabolic side effects of therapy because of its potential impact on growth and the children's likely greater cumulative exposure. This review summarizes the epidemiology and management of lipodystrophy, dyslipidemia, insulin resistance, hyperlactatemia, osteopenia and growth failure in HIV-infected children.
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页码：77 / 84
页数：8
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