High-Dose Chemotherapy and Autologous Stem Cell Transplant

被引：5

作者：

Adra, Nabil ^{[1
]}

Abonour, Rafat ^{[1
]}

机构：

[1] Indiana Univ Sch Med, Melvin & Bren Simon Canc Ctr, Div Hematol & Med Oncol, 535 Barnhill Dr,RT 400, Indianapolis, IN 46202 USA

来源：

UROLOGIC CLINICS OF NORTH AMERICA | 2019年 / 46卷 / 03期

关键词：

Testicular cancer; Germ cell tumor; High-dose chemotherapy; Salvage chemotherapy; Stem cell transplant; CISPLATIN-BASED CHEMOTHERAPY; TESTICULAR CANCER SURVIVORS; IFOSFAMIDE PLUS CISPLATIN; PROGNOSTIC-FACTORS; SALVAGE TREATMENT; RANDOMIZED-TRIAL; TUMOR PATIENTS; PHASE-I/II; CARBOPLATIN; PACLITAXEL;

D O I：

10.1016/j.ucl.2019.04.007

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Germ cell tumors (GCT) are the most common cancer in men between 15 and 35 years of age and the incidence has increased during the past several decades. This article reviews the current knowledge on high-dose chemotherapy (HDCT) and stem cell transplant for salvage treatment of patients with relapsed metastatic GCT. Furthermore, the authors attempt to dissect the controversy of using standard-dose versus high-dose therapy as initial salvage and identify patients who are most likely to benefit from HDCT and peripheral blood stem cell transplant.

引用

收藏

页码：439 / +

页数：12

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