One-pot synthesis of pyrano[3,2-c]pyran derivatives catalyzed by KF/Al2O3

被引：49

作者：

Wang, Xiang-Shan ^{[1
]}

Zhou, Jie-Xing

Zeng, Zhao-Sen

Li, Yu-Ling

Shi, Da-Qing

Tu, Shu-Jiang

机构：

[1] Xuzhou Normal Univ, Dept Chem, Xuzhou Jiangsu 221116, Peoples R China

[2] Key Lab Biotechnol Med Plant, Jiangsu 221116, Xuzhou, Peoples R China

来源：

ARKIVOC | 2006年

关键词：

pyrano[3,2-c]pyran; KF/Al2O3; synthesis;

D O I：

10.3998/ark.5550190.0007.b10

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of pyrano[3,2-c] pyran derivatives have been synthesized by the reaction of aromatic aldehyde, malononitrile or cyanoacetate and 4-hydroxy-5-methylpyran-2-one in EtOH at room temperature catalyzed by KF/Al2O3. The structures of the products were characterized by IR, H-1 NMR and elemental analysis, and 4a was further confirmed by X-ray diffraction analysis.

引用

页码：107 / 113

页数：7

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