One-pot synthesis of pyrano[3,2-c]pyran derivatives catalyzed by KF/Al2O3

被引:49
作者
Wang, Xiang-Shan [1 ]
Zhou, Jie-Xing
Zeng, Zhao-Sen
Li, Yu-Ling
Shi, Da-Qing
Tu, Shu-Jiang
机构
[1] Xuzhou Normal Univ, Dept Chem, Xuzhou Jiangsu 221116, Peoples R China
[2] Key Lab Biotechnol Med Plant, Jiangsu 221116, Xuzhou, Peoples R China
关键词
pyrano[3,2-c]pyran; KF/Al2O3; synthesis;
D O I
10.3998/ark.5550190.0007.b10
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A series of pyrano[3,2-c] pyran derivatives have been synthesized by the reaction of aromatic aldehyde, malononitrile or cyanoacetate and 4-hydroxy-5-methylpyran-2-one in EtOH at room temperature catalyzed by KF/Al2O3. The structures of the products were characterized by IR, H-1 NMR and elemental analysis, and 4a was further confirmed by X-ray diffraction analysis.
引用
收藏
页码:107 / 113
页数:7
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