Interplay of biomaterials and micro-scale technologies for advancing biomedical applications

被引：34

作者：

Khademhosseini, Ali ^{[1
]}

Bettinger, Chris

Karp, Jeffrey M.

Yeh, Judy

Ling, Yibo

Borenstein, Jeffrey

Fukuda, Junji

Langer, Robert

机构：

[1] Harvard Mit Div Hlth Sci & Technol, Cambridge, MA 02139 USA

[2] Harvard Univ, Sch Med, Dept Med, Brigham & Womens Hosp, Boston, MA 02115 USA

[3] MIT, Dept Mat Sci & Engn, Cambridge, MA 02139 USA

[4] MIT, Dept Chem Engn, Cambridge, MA 02139 USA

[5] MIT, Div Biol Engn, Cambridge, MA 02139 USA

[6] MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA

[7] Charles Stark Draper Lab Inc, Cambridge, MA 02139 USA

来源：

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION | 2006年 / 17卷 / 11期

基金：

美国国家卫生研究院; 加拿大自然科学与工程研究理事会;

关键词：

BioMEMS; biomaterials; surface patterning; micro-fluidics; tissue engineering; review;

D O I：

10.1163/156856206778667488

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Micro-scale technologies have already dramatically changed our society through their use in the microelectronics and telecommunications industries. Today these engineering tools are also useful for many biological applications ranging from drug delivery to DNA sequencing, since they can be used to fabricate small features at a low cost and in a reproducible manner. The discovery and development of new biomaterials aid in the advancement of these micro-scale technologies, which in turn contribute to the engineering and generation of new, custom-designed biomaterials with desired properties. This review aims to present an overview of the merger of micro-scale technologies and biomaterials in two-dimensional (2D) surface patterning, device fabrication and three-dimensional (3D) tissue-engineering applications.

引用

页码：1221 / 1240

页数：20

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