Iron-Catalyzed Cycloaddition of Amides and 2,3-Diaryl-2H-azirines To Access Oxazoles via C-N Bond Cleavage

被引：9

作者：

Zhao, Mi-Na ^{[1
]}

Ning, Gui-Wan ^{[1
]}

Yang, De-Suo ^{[1
]}

Fan, Ming-Jin ^{[1
]}

Zhang, Sheng ^{[1
]}

Gao, Peng ^{[1
]}

Zhao, Li-Fang ^{[1
]}

机构：

[1] Baoji Univ Arts & Sci, Coll Chem & Chem Engn, Shaanxi Key Lab Phytochem, Baoji 721013, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 86卷 / 03期

基金：

中国博士后科学基金;

关键词：

D O I：

10.1021/acs.joc.0c02843

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and efficient iron-catalyzed cycloaddition reaction using readily available 2,3-diaryl-2H-azirines and primary amides is reported. A wide range of trisubstituted oxazoles could be achieved in good yields with good functional group compatibility. In this transformation, two C-N bonds were cleaed and new C-N and C-O bonds were formed.

引用

页码：2957 / 2964

页数：8

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